Results 21 to 30 of about 23,257 (267)

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

open access: yes, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A.   +4 more
core   +1 more source

Lysyl Oxidases in the Trabecular Meshwork [PDF]

open access: yesJournal of Glaucoma, 2014
The mechanical properties of the extracellular matrix (ECM) play an important role in maintaining cellular function and overall tissue homeostasis. Emerging evidence suggests that biomechanical modifications of the ECM may be initiators and/or drivers of disease, exemplified by increased tissue stiffness.
Robert J, Wordinger, Abbot F, Clark
openaire   +2 more sources

The Effect of Hyaluronic Acid on MMP-9 Expression in Trabecular Meshwork Cell Culture of Patient with Primary Open Angle Glaucoma

open access: yesJournal of Agromedicine and Medical Sciences (AMS), 2017
In primary open angle glaucoma, decrease of hyaluronic acid level is related to extracellular matrix deposition of trabecular meshwork. Extracellular matrix deposition will increase humor aqueous outflow resistance which in turn increase the intraocular ...
Cicih Komariah   +2 more
doaj   +1 more source

Association between Myopia, Biometry and Occludable Angle: The Jiangning Eye Study. [PDF]

open access: yesPLoS ONE, 2016
Myopia subjects usually have long axial lengths and are predisposed to deep anterior chamber depths and open angles. Jiangning eye study is a randomized, population based study in Shanghai to determine whether myopia has an effect on the prevalence of ...
Xiaohong Liu   +9 more
doaj   +1 more source

The intrinsic stiffness of human trabecular meshwork cells increases with senescence. [PDF]

open access: yes, 2015
Dysfunction of the human trabecular meshwork (HTM) plays a central role in the age-associated disease glaucoma, a leading cause of irreversible blindness.
Chang, Yow-Ren   +4 more
core   +3 more sources

Trabecular meshwork gene expression after selective laser trabeculoplasty.

open access: yesPLoS ONE, 2011
BackgroundTrabecular meshwork and Schlemm's canal are the tissues appointed to modulate the aqueous humour outflow from the anterior chamber. The impairment of their functions drives to an intraocular pressure increase.
Alberto Izzotti   +4 more
doaj   +1 more source

Implantation of trabecular micro-bypass stent using a novel “landing strip” technique [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To describe a novel technique of creating a landing strip within the trabecular meshwork to guide trabecular micro-bypass stent (iStent) implantation in patients who underwent phacoemulsification.
Cindy X. Zheng   +5 more
doaj   +1 more source

Morphological changes in the iridocorneal angle and their relationship with intraocular pressure after infantile cataract surgery [PDF]

open access: yesInternational Journal of Ophthalmology, 2022
AIM: To evaluate morphological changes in the iridocorneal angle after pediatric cataract surgery. METHODS: Children who underwent primary infantile cataract surgery were included and 64 eyes from 41 children, including 18 with unilateral cataracts (18 ...
Dan-Dan Wang   +5 more
doaj   +1 more source

Canaloplasty in the Treatment of Open-Angle Glaucoma: A Review of Patient Selection and Outcomes. [PDF]

open access: yes, 2018
Canaloplasty is a relatively new non-penetrating surgery for the reduction of intraocular pressure in patients affected by glaucoma. The technique uses a microcatheter to perform a 360 º cannulation of Schlemm's canal and leaves in place a tension suture
Brusini, Paolo   +5 more
core   +2 more sources

Human trabecular meshwork cell volume regulation [PDF]

open access: yesAmerican Journal of Physiology-Cell Physiology, 2002
The volume of certain subpopulations of trabecular meshwork (TM) cells may modify outflow resistance of aqueous humor, thereby altering intraocular pressure. This study examines the contribution that Na+/H+, Cl−/HCO[Formula: see text]exchange, and K+-Cl− efflux mechanisms have on the volume of TM cells.
Claire H, Mitchell   +4 more
openaire   +2 more sources

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