Results 41 to 50 of about 16,541 (253)
PLoS ONE, 2011 BackgroundOpen-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment.
Alberto Izzotti +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Surgery on the Trabecular Meshwork: Histopathological Evidence
, 2015 Juxtacanalicular (JXT) trabecular meshwork and endothelial lining of Schlemm's canal have been cited as the loci of aqueous outflow resistance, both in a normal as well as a glaucomatous eye.
Ichhpujani, Parul +2 more
core +1 more source
A Practice Model for Trabecular Meshwork Surgery [PDF]
Archives of Ophthalmology, 2009 Models for practicing ophthalmic surgery are a necessary part of all ophthalmic training. Herein, we describe a method for preparing human donor cadaveric eyes with direct visualization of the anterior chamber angle for practicing trabecular meshwork surgery. This model can be adapted for use with both fresh and formalin-fixed eyes. The use of formalin-
Sangita P, Patel, Arthur J, Sit
openaire +2 more sources
Advanced Materials, EarlyView.This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang +10 more
wiley +1 more source
Re-thinking the trabecular meshwork anatomy-A histopathological analysis
Indian Journal of Ophthalmology. Case ReportsThe trabecular meshwork serves as the primary site for regulating the outflow of aqueous humor from the eye. In glaucoma, dysfunction or structural abnormalities within the trabecular meshwork can impede the normal flow of aqueous humor, leading to ...
Aparna Rao
doaj +1 more source
Functional properties of fibronectin in the trabecular meshwork [PDF]
Experimental Eye Research, 2009 Fibronectin plays a number of important roles in the extracellular matrix (ECM) including providing structural support and signaling cues for cell survival, migration, differentiation, gene expression, growth factor signaling, and cell contractility.
Jennifer A, Faralli +4 more
openaire +2 more sources
Advanced Materials, EarlyView.A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu +7 more
wiley +1 more source
Glycosaminoglycans in human trabecular meshwork: Age-related changes
, 2004 Glycosaminoglycans play a central role in maintaining the normal outflow resistance in the human trabecular meshwork. We evaluated the possible morphological, histochemical and morphometrical age-related changes in glycosaminoglycans of the trabecular ...
SAGNELLI, Paolo +6 more
core +1 more source
Cystatin a, a potential common link for mutant myocilin causative glaucoma.
PLoS ONE, 2012 Myocilin (MYOC) is a 504 aa secreted glycoprotein induced by stress factors in the trabecular meshwork tissue of the eye, where it was discovered. Mutations in MYOC are linked to glaucoma.
K David Kennedy +3 more
doaj +1 more source