Results 41 to 50 of about 23,257 (267)
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure. [PDF]
, 2017 Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a leading cause of blindness. IOP heritability has been estimated to up to 67%, and to date only 11 IOP loci have been reported, accounting for 1.5% of IOP variability.
Banda, Yambazi +10 more
core +3 more sources
Mechanism of Secondary Glaucoma Development in HTLV-1 Uveitis
Frontiers in Microbiology, 2022 Human T-cell lymphotropic virus type 1 (HTLV-1) was the first retrovirus identified as the causative agent of human diseases, such as adult T-cell leukemia, HTLV-1-associated myelopathy, and HTLV-1 uveitis (HU).
Yuan Zong +4 more
doaj +1 more source
A porcine ex vivo model of pigmentary glaucoma [PDF]
, 2017 Pigment dispersion syndrome can lead to pigmentary glaucoma (PG), a poorly understood condition of younger, myopic eyes with fluctuating, high intraocular pressure (IOP).
Dang, Yalong +5 more
core +2 more sources
PLoS ONE, 2011 BackgroundOpen-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment.
Alberto Izzotti +3 more
doaj +1 more source
Biological properties of trabecular meshwork cells [PDF]
Experimental Eye Research, 2009 The molecular and physiological mechanisms that lead to the progression of glaucoma are poorly understood. Despite the fact that glaucoma afflicts millions of people worldwide, research on the disease is limited by the current animal models that do not translate well to human forms of the disease.
Joshua Z, Gasiorowski, Paul, Russell
openaire +2 more sources
Differential Protein Expression Profiles in Glaucomatous Trabecular Meshwork: An Evaluation Study on a Small Primary Open Angle Glaucoma Population [PDF]
, 2016 INTRODUCTION: Primary open angle glaucoma (POAG) is a progressive optic neuropathy characterized by impaired aqueous outflow and extensive remodeling in the trabecular meshwork (TM).
Esposito, Graziana +8 more
core +1 more source
Stress Response of the Trabecular Meshwork [PDF]
Journal of Glaucoma, 2008 The trabecular meshwork (TM) is known to be subjected to different types of stress such as mechanical, oxidative, and phagocytic stress. Although short-term exposure to these stresses is expected to elicit adaptive responses, long-term exposure may lead to permanent alterations in the tissue physiology and contribute to the pathologic increase in ...
Paloma B, Liton, Pedro, Gonzalez
openaire +2 more sources
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Gene transfer to human trabecular meshwork cells in vitro and ex vivo using HIV-based lentivirus [PDF]
, 2014 AIM:To investigate whether the enhanced green fluorescent protein (EGFP) reporter gene could be transferred into human trabecular meshwork (HTM) cells by a HIV-based lentivirus both in vitro and ex vivo.
Li, Bin +6 more
core +2 more sources
Senescence in cultured trabecular meshwork cells [PDF]
British Journal of Ophthalmology, 2007 It has been suggested that replicative senescence might be involved in the pathophysiology of age-related diseases.To study the process of senescence in trabecular meshwork (TM) cells.Porcine TM tissues were obtained and placed in primary cultures with Dulbecco's modified Eagle's medium/Ham's F-12 medium.
Yukari, Yamazaki +8 more
openaire +2 more sources