Results 51 to 60 of about 23,257 (267)

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Cystatin a, a potential common link for mutant myocilin causative glaucoma.

PLoS ONE, 2012
Myocilin (MYOC) is a 504 aa secreted glycoprotein induced by stress factors in the trabecular meshwork tissue of the eye, where it was discovered. Mutations in MYOC are linked to glaucoma.
K David Kennedy, S A AnithaChristy, Lakisha K Buie, Teresa Borrás   +3 more
doaj   +1 more source

An Iconic Case of Pigmentary Glaucoma: Brief Review of the Literature

Case Reports in Ophthalmology, 2020
Pigment dispersion syndrome and pigmentary glaucoma are two conditions characterized by pigment dispersion originating from the posterior part of the iris and its accumulation on the trabecular meshwork, corneal endothelium, and anterior surface of the ...
Mariachiara Di Pippo, Chiara Ciancimino, Luca Scuderi, Andrea Perdicchi   +3 more
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

CRISPR-Cas9–based treatment of myocilin-associated glaucoma [PDF]

, 2018
Primary open-angle glaucoma (POAG) is a leading cause of irreversible vision loss worldwide, with elevated intraocular pressure (IOP) a major risk factor. Myocilin (MYOC) dominant gain-of-function mutations have been reported in ∼4% of POAG cases.
Bugge, Kevin, Clark, Abbot F., Fingert, John H., Jain, Ankur, Kasetti, Ramesh B., Ran, Fei, Searby, Charles C., Sharma, Tasneem P., Sheffield, Val C., Yan, Winston Xia, Zhang, Feng, Zode, Gulab   +11 more
core   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

Advanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro, Mario González‐Quintas, Mónica Fernández‐Arias, Jesús del Val, Félix Quintero, Rafael Comesaña, Fernando Lusquiños, Julian R. Jones, Juan Pou   +8 more
wiley   +1 more source

Corneal alterations associated with pseudoexfoliation syndrome and glaucoma: A literature review [PDF]

, 2017
A systematic literature review was performed evaluating articles examining the effects of pseudoexfoliation syndrome (PEX) and glaucoma (PEXG) on the cornea with a focus on the corneal endothelium.
Palko, Joel R, Qi, Owen, Sheybani, Arsham   +2 more
core   +7 more sources

A laser-induced mouse model with long-term intraocular pressure elevation [PDF]

, 2014
Purpose: To develop and characterize a mouse model with intraocular pressure (IOP) elevation after laser photocoagulation on the trabecular meshwork (TM), which may serve as a model to investigate the potential of stem cell-based therapies for glaucoma ...
Du, Y, Fu, V, Kagemann, L, Lathrop, KL, Schuman, JS, Stolz, DB, Sun, M, Yang, E, Yun, H   +8 more
core   +3 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Pigmented lesion in the anterior chamber angle following multiple trans-scleral diode laser photocoagulation for congenital glaucoma

American Journal of Ophthalmology Case Reports, 2019
Purpose: To describe a child with primary congenital glaucoma found to have pigment tissue proliferation in the angle following multiple applications of trans-scleral cyclophotocoagulation. Observations: During examination under anaesthesia, a 4-year-old
Mamdouh Al-Tamimi, Rizwan Malik, Deepak P. Edward   +2 more
doaj   +1 more source