Results 161 to 170 of about 57,744 (244)

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

From Synthesis to Mechanism: Biological Evaluation of a p-Toluidine-Based Thiazolidinone-Quinoline VEGFR-2 Candidate Supported by CADD. [PDF]

Int J Mol Sci
Manni E, Hussein MF, Elkady S, Abdel-Rahman AA, Hawata MA, El-Sayed WA, El-Sayed AF, El-Hema HS.   +7 more
europepmc   +1 more source

Non‐Hermitian Stealthy Hyperuniformity

Advanced Science, EarlyView.
A framework for non‐Hermitian extensions of hyperuniformity and stealthiness is proposed, generalizing PT‐symmetric gain‐loss crystals to correlated disorder in the weak‐scattering limit. By engineering real‐imaginary correlations of the material potential, this framework enables directional scattering phases inaccessible in Hermitian materials ...
Gitae Lee, Seungmok Youn, Ikbeom Lee, Kunwoo Park, Duhwan Hwang, Seungkyun Park, Xianji Piao, Namkyoo Park, Sunkyu Yu   +8 more
wiley   +1 more source

Enhancing the specificity of gene editing outcomes by using Cas9 variants in porcine embryos. [PDF]

J Anim Sci
Kim J, Yoon J, Chen J, Lee J, Lee HJ, Whitworth K, Redel B, Prather RS, Lee K.   +8 more
europepmc   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Intermolecular Electrophilic Germylation Using GeCl₄ and Al₂Cl₆. [PDF]

Angew Chem Int Ed Engl
Łosiewicz J, Bisai MK, Bub ZA, Macgregor SA, Ingleson MJ.   +4 more
europepmc   +1 more source

Anomalous Enhancement in MXene‐Based Electrochemical Actuators: Pseudo‐Capacitance‐Induced Multi‐Charge Accumulation in Confined Space

Advanced Science, EarlyView.
We elucidate the electrochemical actuation mechanism of 2D material‐based electrodes within a MXene‐centered framework, linking atomic‐scale surface chemistry to macroscopic performance (see schematic). Mechanistically, the reduction of Ti─O─Ti sites in H2SO4 triggers the accumulation of hydrated ions at confined active sites, resulting in anomalous ...
Jiang Xu, Jipeng Feng, Bingqing Hu, Xude Li, Shifei Huang, Shanhai Ge, Guoxiu Wang   +6 more
wiley   +1 more source

Synthesis of Li₁₀GeP₂S₁₂ Electrolyte Using Aqueous Solution. [PDF]

J Am Chem Soc
Hashii T, Tanigaki H, Sakashita H, Kowada H, Motohashi K, Sakuda A, Hayashi A.   +6 more
europepmc   +1 more source

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Advanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi, Nicolas Carvalho, Jacinthe Frangieh, Corentin Léger, Dorothée Raoux‐Barbot, J. Iñaki Guijarro, Daniel Ladant, Sophie Cribier, Nicolas Rodriguez, Alexandre Chenal   +9 more
wiley   +1 more source

Spatiotemporal patterns and clustering of prostate cancer incidence in China: a Bayesian modeling study of cancer registry data. [PDF]

BMC Public Health
Zhu X, Chen Z, Ge MW, Rehman AU, Chen HL, Zhu H, Zheng B.   +6 more
europepmc   +1 more source