Results 41 to 50 of about 890,367 (277)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

open access: yesArthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

The Impact of Open Innovation within Technology Parks: Dokuz Eylül Technology Development Zone Analysis

open access: yesİzmir İktisat Dergisi, 2020
İnovasyon ve Ar-Ge, ülkelerin gelişmişlik düzeylerinin ve ekonomisinin değer kazanması açısından büyük önem taşımaktadır. Türkiye’de teknoloji geliştirme bölgelerinde Ar-Ge ekosisteminin gelişimi hızla artarak devam etmektedir. Çalışmamız genel olarak Ar-
Muratcan Karagöz   +2 more
doaj   +1 more source

Türkiye'de AR-GE çalışmaları ve AR-GE'nin Türkiye ekonomisine etkisi [PDF]

open access: yes, 1998
Tez (yüksek lisans) - Anadolu ÜniversitesiAnadolu Üniversitesi, Sosyal Bilimler Enstitüsü, İktisat Anabilim DalıKayıt no: 133564İktisadi gelişmenin en önemli unsurlarından biri sanayileşmek ise sanayileşmenin devamlı ve yayılgan bir yapı kazanması içinde
Özenç, Mustafa
core  

SİPARİŞ ÜZERİNE YAPILAN AR-GE PROJELERİ VE MUHASEBE SÜRECİNİN İNCELENMESİ

open access: yes, 2021
Teknolojik yeniliğin gerçekleştirilmesi ancak Araştırma ve Geliştirmefaaliyeti ile mümkün olabilir. Ar-Ge çalışmaları genel olarak uzun sürealabilir, harcama ve uğraş gerektirir, başarısızlıkla sonuçlanabilir.
Kaya, Kamber
core  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Low‐Cost, Large‐Scale Nanoporous Metals by Mechanical Alloying, Oxide Reduction, and Dealloying of Powders

open access: yesAdvanced Engineering Materials, EarlyView.
Powder metal processing provides scalable advantages in nanoporous (np) metal development. Mechanical alloying is used to produce unique precursors for hybrid nanopore formation by oxide reduction and dealloying. As demonstrated in np Ag, this approach improves process efficiency while promoting smaller ligaments and larger pores, both of which are ...
Mark A. Atwater, Oliver A. Fowler
wiley   +1 more source

Low‐Angle Grain Boundaries and Re‐Segregation in Single‐Crystalline Ni‐Base Superalloys

open access: yesAdvanced Engineering Materials, EarlyView.
This work demonstrates that Re‐segregation at low‐angle grain boundaries (LAGBs) in Ni‐base superalloys is influenced by misorientation angle. Advanced microscopy and atom probe tomography reveal that higher misorientation angles increases Re‐segregation.
Alireza B. Parsa   +9 more
wiley   +1 more source

Recycling of NiTi Shape Memory Alloys: Fundamental and Technological Aspects of a Vacuum Induction Melting Processing Route

open access: yesAdvanced Engineering Materials, EarlyView.
The present study investigates recycling of NiTi shape memory alloys via vacuum induction melting. An ingot was synthesized from elemental Ni and Ti and subjected to three subsequent remelting cycles. Remelting increases process durations and impurity levels and adversely affects microstructures and functional properties.
Sakia Sophia Noorzayee   +7 more
wiley   +1 more source

Ar-Ge yönetimi ve KOBİ`lerde Ar-Ge faaliyetleri

open access: yes, 2021
The subject of this study is R&D Management and KOBI applications.Study is realized in two steps. First step depends mainiy on literaturalresearehes. On the other hand the second step is related with a study.The R&D concept and definition in Turkey is poor.
openaire   +1 more source

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