Results 41 to 50 of about 1,217,652 (278)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Teknopark İşletmelerinde Ürün Ticarileştirme ve Pazarlama Yetkinliği Boyutlarının ve Yeterliliklerinin Belirlenmesine Yönelik Bir Araştırma

Online Academic Journal of Information Technology, 2019
İnovasyon ve ar-ge odaklı rekabet edebilirlik için etkin bir iletişim ve etkileşim ağı ile birbirine bağlanmış ekosistemlerin oluşturulması oldukça önemlidir.
Yahya Özdemir, Kazım Karaboğa
doaj   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine, Fabien Rollot, Romain Casey, Nicolas Collongues, Sandra Vukusic, Guillaume Mathey, Anne Laure Dubessy, Jonathan Ciron, Jérôme De Seze, Aurélie Ruet, Pierre Labauge, Arnaud Kwiatkowski, Hélène Zephir, Caroline Papeix, Gilles Defer, Christine Lebrun‐Frenay, David Axel Laplaud, Eric Berger, Eric Thouvenot, Jean Pelletier, Abdullatif Al Khedr, Olivier Casez, Bertrand Bourre, Abir Wahab, Laurent Magy, Jean‐Philippe Camdessanché, Ines Doghri, Solène Moulin, Mariana Sarov Rivière, Karolina Hankiewicz, Amélie Dos Santos, Corinne Pottier, Eric Manchon, Jennifer Aboab, Maia Tchikviladze, Thomas David, Gilles Edan, Emmanuelle Le Page, Laure Michel, Anne Kerbrat, OFSEP Investigators   +40 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

AlSi12 Alaşımından Üretilen Kompresör Silindir Kapağında Abrasif Aşınma Davranışının İncelenmesi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2017
Bu çalışmada havalı fren kompresör silindir kafası üretiminde kullanılan aynı kimyasal bileşime sahip fakat farklı morfolojide iki farklı AlSi12 alaşımının aşınma dirençleri incelenmiştir.
Samet Aksoy, Erdem Ünüvar, Mustafa Acarer   +2 more
doaj   +4 more sources

OECD ÜLKELERİNDE KAMU AR-GE POLİTİKALARININ ÖZEL SEKTÖR AR-GE YOĞUNLUĞUNA ETKİLERİ: PANEL EŞİK MODELİNDEN KANITLAR [PDF]

, 2023
Kamu ar-ge politikaları, özel sektör ar-ge yoğunluğunu artırmak, harekete geçirmek amacıyla 20.yy. ortalarından itibaren yoğun şekilde kullanılmıştır.

core  

Investigating the Effect of Inclination Angle and the Influence of Scan Parameters on the Appearance and Thermal and Mechanical Properties of Filigree Tension Rods of LPBF‐Manufactured NiTi Shape‐Memory Alloys

Advanced Engineering Materials, EarlyView.
This article investigates the dependence of the properties on the manufacturing orientation in the form of the inclination angle to the build plate of LPBF‐fabricated NiTi rods with a diameter of 150–220 µm. Metallographic, chemical, thermal, and mechanical characterization show behavior under identical manufacturing conditions that ranges from ...
Sandra Herzig, Michael Werner, Christian Rotsch   +2 more
wiley   +1 more source

Control of Polarization and Polar Helicity in BiFeO3 by Epitaxial Strain and Interfacial Chemistry

Advanced Functional Materials, EarlyView.
In BiFeO3 thin films, the interplay of interfacial chemistry, electrostatics, and epitaxial strain is engineered to stabilize homohelicity in polarization textures at the domain scale. The synergistic use of a Bi2O2‐terminated Aurivillius buffer layer and a highly anisotropic compressive epitaxial strain offers new routes to control the polar‐texture ...
Elzbieta Gradauskaite, Lilia Huynh, Natascha Gray, Quintin N. Meier, Marta D. Rossell, Morgan Trassin   +5 more
wiley   +1 more source

YÜKSELEN EKONOMİLERDE ELEKTRİK TÜKETİMİNİN YENİLİK VE TEKNOLOJİ GÖSTERGELERİ KAPSAMINDA ANALİZİ

KAÜ-İİBF Dergisi, 2019
Bu çalışmada 2000-2018 dönemi için gelişmekte olan ülkelerde patent başvuru sayısı, kişi başına Ar-Ge harcaması, mobil hat abone sayısı ve internet kullanıcı sayısı gibi yenilik ve teknoloji göstergelerinin kişi başına elektrik tüketimine olan etkileri ...
Bayram Veli Doyar, Eser Çapık, Zeynep Ezanoğlu, Yunus Kutval   +3 more
doaj   +1 more source