Results 91 to 100 of about 7,460,800 (333)

Characterization of a monoclonal antibody that induces the acrosome reaction of sea urchin sperm. [PDF]

open access: yes, 1987
A monoclonal antibody, J18/29, induces the acrosome reaction (AR) in spermatozoa of the sea urchin Strongylocentrotus purpuratus. J18/29 induces increases in both intracellular Ca2+ and intracellular pH similar to those occurring upon induction of the AR
Ebina, Y   +4 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

TRIM16 transcription factor in prostate cancer

open access: yesБюллетень сибирской медицины, 2018
The aim of this investigation was to reveal the expression TRIM16, ERα, ERβ and AR in prostate cancer tissues compared to benign hyperplasia and clinical and morphological parameters.Materials and methods.
L. V. Spirina   +5 more
doaj   +1 more source

PERANCANGAN BUKU ELEKTRONIK PADA PELAJARAN MATEMATIKA BANGUN RUANG SEKOLAH DASAR BERBASIS AUGMENTED REALITY

open access: yesSimetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2020
Augmented Reality (AR) Book dapat digunakan sebagai langkah dalam meningkatkan pembelajaran dan pengajaran di sekolah dasar. Hal ini disebabkan AR dapat memberikan siswa kemampuan untuk belajar yang interaktif di berbagai tempat serta waktu yang mereka ...
Qadhli Jafar Adrian   +2 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Perceptual effects of modified late reverberation and reverberation time in auditory augmented reality in two rooms

open access: yesActa Acustica
This paper presents two experiments investigating perceptual tolerances regarding deviations in the late reverberation of a room in augmented reality (AR) audio rendering.
Schneiderwind Christian   +2 more
doaj   +1 more source

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. [PDF]

open access: yes, 2014
Macroautophagy (hereafter autophagy) is a key pathway in neurodegeneration. Despite protective actions, autophagy may contribute to neuron demise when dysregulated.
Batlevi, Yakup   +11 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Application prospect analysis of augmented reality technology in mine ventilation system

open access: yesGong-kuang zidonghua, 2018
Basic concept and features of augmented reality technology were introduced, idea of applying augmented reality technology to mine ventilation system was proposed combining with development trend of smart mines in China.
CHENG Donghao, HUN Baoju, JIN Kai
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Home - About - Disclaimer - Privacy