Results 71 to 80 of about 7,402,456 (286)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Learning Experience Design: Embodiment, Gesture, and Interactivity in XR
Educational Technology & Society, 2021 The concepts of embodiment and embodied learning are gaining traction in the field of education. This special issue aims to synthesize current knowledge on the design and evaluation of learning in immersive and embodied learning environments, mediated by
Andri Ioannou +2 more
doaj
A Fire Reconnaissance Robot Based on SLAM Position, Thermal Imaging Technologies, and AR Display
Sensors, 2019 Due to hot toxic smoke and unknown risks under fire conditions, detection and relevant reconnaissance are significant in avoiding casualties. A fire reconnaissance robot was therefore developed to assist in the problem by offering important fire ...
Sen Li +5 more
doaj +1 more source
, 2003 We observed the coronally active eclipsing binary, AR Lac, with the High Energy Transmission Grating on Chandra for a total of 97 ks, spaced over five orbits, at quadratures and conjunctions.
Bowyer S. +22 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Journal of Integrative Bioinformatics, 2019 Gene expression studies revealed a large degree of variability in gene expression patterns particularly in tissues even in genetically identical individuals. It helps to reveal the components majorly fluctuating during the disease condition.
Asati Nimisha +3 more
doaj +1 more source
Água e ar em uma cidade higiênica, asséptica, inodora
Revista Brasileira de História da Ciência, 2018 Este artigo busca problematizar aspectos que atravessaram a reordenação de espaços urbanos na viragem do século XIX para o XX. Tendo Belo Horizonte como referência, elenca questões que estiveram presentes nas discussões a respeito da construção de uma ...
Verona Campos Segantini
doaj +1 more source
Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland [PDF]
, 2019 The evidence from post-mortem biochemical studies conducted on cortisol and catecholamines suggest that analysis of the adrenal gland could provide useful information about its role in human pathophysiology and the stress response.
Alibrandi A. +10 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Études littéraires, 2005 Au Moyen Âge, la Musique chante l'unité du savoir et de l'être. Quand, au XIV e siècle, être et savoir se distancient l'un de l'autre, entraînant avec eux théorie et pratique, matière et forme, la «littérature» émergente joue un rôle d'articulation entre ces dichotomies.
openaire +2 more sources