Results 61 to 70 of about 7,402,456 (286)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cancer Management and Research, 2020 Xiangyu Zhang,1,* Yanmin Zhang,2,* Fanzhong Lin,1 Xin Shi,1 Longquan Xiang,1 Liang Li1 1Department of Pathology, Jining First People’s Hospital, Jining Medical University, Jining 272000, People’s Republic of China; 2Department of Pathology ...
Zhang X +5 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Barekeng, 2020 Crime is a crime that violates the laws of a country or violates the norms in force in society. Theft is a form of crime. The impact of theft is a feeling of insecurity, fear and insecurity. One model used to predict the number of theft cases is the time
Meli Pranata +3 more
doaj +1 more source
Peptides disrupting TM4SF3 interaction with AR or AR-V7 block prostate cancer cell proliferation
Endocrine Oncology, 2023 Androgen receptor (AR) plays a vital role in the development and progression of prostate cancer from the primary stage to the usually lethal stage known as castration-resistant prostate cancer (CRPC).
Prabesh Khatiwada +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
AR moulded-objects performing Giuseppe Verdi's 200th birthday
Archeomatica, 2014 "Muri e Divisioni" è una mostra collettiva di arte contemporanea. Una call for artists è stata organizzata da Accademia delle Arti di Macerata, un'organizzazione locale no-profit composta da 40 artisti, per raccogliere opere adeguate per la mostra.
Giuliana Guazzaroni, Mirco Compagno
doaj
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Arte e tecnica materiale nell’Encyclopédie [PDF]
S&F_scienzaefilosofia.it, 2018 Art and material technology in the Encyclopédie The Diderot’s article Art of the Encyclopédie is not only an essay about the classic division between liberal and mechanical arts but also a new way of advocating the second ones.
Cosenza, Mario
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Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides [PDF]
, 2012 Copyright @ 2012 National Institute of Environmental Health Sciences.This article has been made available through the Brunel Open Access Publishing Fund.Background: Many pesticides in current use have recently been revealed as in vitro androgen receptor (
Andreas Kortenkamp +4 more
core +1 more source