Results 191 to 200 of about 116,348 (354)

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij   +7 more
wiley   +1 more source

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer   +2 more
wiley   +1 more source

DASH: a versatile and high‐capacity gene stacking system for plant synthetic biology

open access: yesPlant Biotechnology Journal, EarlyView.
Summary DNA assembly systems based on the Golden Gate method are popular in synthetic biology but have several limitations: small insert size, incompatibility with other cloning platforms, DNA domestication requirement, generation of fusion scars, and lack of post‐assembly modification.
Chengsong Zhao   +2 more
wiley   +1 more source

Metabolism of l-arabinose converges with virulence regulation to promote enteric pathogen fitness

open access: yesNature Communications
Virulence and metabolism are often interlinked to control the expression of essential colonisation factors in response to host-associated signals. Here, we identified an uncharacterised transporter of the dietary monosaccharide ʟ-arabinose that is widely
Curtis Cottam   +7 more
doaj   +1 more source

SYNTHESIS OF 5-PHOSPHO-d-ARABINOSE

open access: hybrid, 1938
P.A. Levene, Clarence C. Christman
openalex   +1 more source

Unveiling the catalytical roles of three glycosyltransferases in triterpenoid saponins in quinoa

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Saponins constitute a class of characteristic compounds within quinoa grains. In this study, metabolomic analysis identified 20 triterpene saponins, the majority of which were exclusively localized within the pericarp. Furthermore, three crucial glycosyltransferases were identified in quinoa.
Yiming Zhang   +14 more
wiley   +1 more source

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