Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size [PDF]
Calcium-independent phospholipase A(2)γ (iPLA(2)γ) is a mitochondrial enzyme that produces lipid second messengers that facilitate opening of the mitochondrial permeability transition pore (mPTP) and contribute to the production of oxidized fatty acids ...
Abendschein, Dana +12 more
core +2 more sources
Bone resorption requires cooperation between osteoclasts and mononuclear accessory cells by mechanisms which have not been elucidated. Since multinucleated cells in giant cell tumors of bone have many phenotypic and functional characteristics of normal osteoclasts, we have examined the interaction between the bone-resorbing multinucleated cells and the
W E, Gallwitz +7 more
openaire +2 more sources
Nonsteroidal Anti-Inflammatory Agents in the Therapy for Experimental Pneumococcal Meningitis [PDF]
An increased inflammatory mass in the subarachnoid space during bacterial meningitis may correlate with a poor outcome of disease. Using a rabbit model of pneumococcal meningitis, we sought to reduce this inflammatory process.
Bray, Michael A. +5 more
core
LTC4 synthase polymorphism modifies efficacy of botanical seed oil combination in asthma [PDF]
Botanical seed oils reduce the generation of leukotrienes in patients with asthma. Our objective was to determine the efficacy of a botanical seed oil combination against airflow obstruction in asthma, and to determine the pharmacogenomic effect of the ...
Ainsworth, Hannah C +11 more
core +2 more sources
Source of endogenous arachidonate and 5-lipoxygenase products in human neutrophils stimulated by bradykinin and A23187. [PDF]
Ole Haagen Nielsen +3 more
openalex +1 more source
Expresión diferencial de genes en Pyropia columbina (Bangiales, Rhodophyta) bajo hidratación y desecación natural [PDF]
Indexación: Web of Science; Scielo.RESUMEN. En Zonas Costeras rocosas, la desecación es gatillada porción Cambios Diarios en los Niveles de marea, y la Evidencia indica experimental de Me Distribución de las algas en la zona intermareal no está ...
Contreras-Porcia, Loretto +10 more
core
RELATIONSHIP OF THE SERUM LEUKOTRIENE B4 LEVEL WITH THE RISK OF UNSTABLE ANGINA PECTORIS AND THE ARACHIDONATE 5-LIPOXYGENASE ACTIVATING PROTEIN GENE SG13S114T/A POLYMORPHISM [PDF]
Guoping He +5 more
openalex +1 more source
Dimerization of human 5-lipoxygenase [PDF]
Human 5-lipoxygenase (5-LO) can form dimers as shown here via native gel electrophoresis, gel filtration chromatography and LILBID (laser induced liquid bead ion desorption) mass spectrometry.
Brutschy, Bernhard +8 more
core
Multi-walled carbon nanotubes induce arachidonate 5-lipoxygenase expression and enhance the polarization and function of M1 macrophages in vitro [PDF]
Chol Seung Lim +4 more
openalex +1 more source
RELATIONSHIP OF ARACHIDONATE 5-LIPOXYGENASE ACTIVATING PROTEIN GENE SG13S114T/A POLYMORPHISM WITH ACUTE MYOCARDIAL INFARCTION [PDF]
Guoping He +3 more
openalex +1 more source

