Results 301 to 310 of about 194,523 (350)
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Arachidonic acid production by microorganisms
Biotechnology and Applied Biochemistry, 1992Arachidonic acid (AA) is a natural precursor of prostaglandins, thromboxanes, leukotrienes, prostacyclins, and a large group of C20 compounds which are of intrinsic medical interest. At present, the only source of AA is animal tissues. However, it is present in several microorganisms. This review describes the production of AA by microorganisms and its
P, Bajpai, P K, Bajpai
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Arachidonic acid aggregates neutrophils
Inflammation, 1979Arachidonic acid, but not several structurally similar fatty acids, stimulated neutrophils in suspension to aggregate; this effect was blocked by 5, 8, 11, 14-eicosatetraynoic acid, an inhibitor of arachidonic acid metabolism. Analagous to platelets, arachidonate may be a precursor of active metabolites which mediate neutrophil responses.
J T, O'Flaherty +3 more
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Renal Arachidonic Acid Metabolism
Annual Review of Physiology, 1984Renal prostaglandin synthesis has been the focus of extensive investigation during the past decade. This chapter reviews the cellular localization of renal arachidonic acid metabolism in view of the substantial recent progress in the isolation and culture of renal cell types.
M G, Currie, P, Needleman
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CHEMIEXCITATION IN THE ARACHIDONIC ACID CASCADE
Photochemistry and Photobiology, 1991Abstract—As investigated in neutrophils, the very weak luminescence accompanying the arachidonic acid cascade is associated with the lipoxygenase pathway. The emission is dramatically enhanced by energy transfer to chlorophylla. The number of chlorophyll molecules excited to the fluorescent state per oxygen consumed, (the S1/O2ratio), equal to the ...
A L, Nascimento, G, Cilento
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Arachidonic acid and colorectal carcinogenesis
Molecular and Cellular Biochemistry, 2003Colorectal carcinoma is a leading cause of cancer related death worldwide. This deadly disease advances through a series of clinical and histopathological stages, initiated by single crypt lesions to small benign tumors and finally to malignancy. Although some progress has been made in elucidating the formation of colorectal tumors at molecular/genetic
Raymond, Jones +4 more
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Interactions of zinc and arachidonic acid
Prostaglandins and Medicine, 1981To probe the interaction of zinc with polyunsaturated fatty acids we have studied the effect of zinc on the cooxygenation of ferrous iron and arachidonic acid. Zinc inhibited the process of cooxygenation in a concentration dependent fashion. Further evaluation of the interaction of zinc and arachidonic acid gave spectroscopic evidence that zinc, oxygen
D A, Peterson +4 more
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Preparation of deuterated arachidonic acid
Prostaglandins, 1981Publisher Summary It is reported preparation of [ 2 H 8 ]arachidonic acid from the precursor tetraacetylene eicosatetraynoic procedures gave rise to substantial double-bond isomerization and isotopic scrambling, leading to mixtures that yielded after purification only small quantities of the desired product.
D F, Taber, M A, Phillips, W C, Hubbard
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Plasma arachidonic acid and the pancreas
Journal of Atherosclerosis Research, 1964Summary This work provides evidence in support of the presence of a factor in the exocrine pancreatic secretion of the dog which regulates the percent composition of plasma arachidonic acid by its action on the cholesterol ester and phospholipid fractions primarily. The factor is distinct from pancreatic enzymes, is heat-stable, and requires adequate
R, CAREN, L, CORBO
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Psoriasis and the arachidonic acid cascade
Journal of Dermatological Science, 1999Arachidonic acid (5.8,11,14-eicosatetraenoic acid C20:4, n-6) is released from the cell membrane by the action of phospholipases on membrane phospholipids. Metabolites of arachidonic acid, which are generically termed eicosanoids, including prostaglandins, thromboxane, leukotrienes and hydroxyeicosatetraenoic acids, have been implicated as mediators or
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Metabolites of arachidonic acid
Clinical Reviews in Allergy, 1983W F, Stenson, C W, Parker
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