Results 321 to 330 of about 5,117,744 (378)

Profiling the response of individual gut microbes to free fatty acids (FFAs) found in human milk. [PDF]

J Funct Foods
Waller ME, Gutierrez A, Ticer TD, Glover JS, Baatz JE, Wagner CL, Engevik MA, Chetta KE.   +7 more
europepmc   +1 more source

Variations in Human Milk Metabolites After Gestational Diabetes: Associations with Infant Growth. [PDF]

Nutrients
Fradet A, Berthiaume L, Laroche LA, Dugas C, Perron J, Doyen A, Audet-Walsh É, Robitaille J.   +7 more
europepmc   +1 more source

Metabolomic Insights into Attention Deficit Hyperactivity Disorder: A Scoping Review. [PDF]

Metabolites
Muñoz-Zabaleta MJ, Garzón Rodríguez N, Díaz-Barrera LE, Quiroz-Padilla MF.   +3 more
europepmc   +1 more source

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The Key Contribution Of Platelet And Vascular Arachidonic Acid Metabolism To The Pathophysiology Of Atherothrombosis.

Cardiovascular Research, 2021
Arachidonic acid is one of the most abundant and ubiquitous ω-6 polyunsaturated fatty acid, present in esterified form in the membrane phospholipids of all mammalian cells and released from phospholipids by several phospholipases in response to various ...
L. Badimón, G. Vilahur, B. Rocca, C. Patrono   +3 more
semanticscholar   +1 more source

Arachidonic Acid Derivatives and Neuroinflammation

CNS & Neurological Disorders - Drug Targets, 2022
: Neuroinflammation is characterized by dysregulated inflammatory responses localized within the brain and spinal cord. Neuroinflammation plays a pivotal role in the onset of several neurodegenerative disorders and is considered a typical feature of these disorders.
Gorica, Era, Calderone, Vincenzo
openaire   +3 more sources

ARACHIDONIC ACID METABOLISM

Annual Review of Biochemistry, 1986
C YC LOO XYGENASE PRODUC TS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . 70 Prostaglandin Endoperoxide Synthase 70 Metabolism of the Prostaglandin Endoperoxides 71 P RODUC TS OF THE 12-LIPO XYGEN ASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Aubrey R. Morrison, John Turk, Philip Needleman, B A Jakschik, J B Lefkowith   +4 more
openaire   +3 more sources

Full Library of (Bis–allyl)-deuterated Arachidonic Acids: Synthesis and Analytical Verification

, 2016
Deuteration at bis-allylic positions slows down hydrogen abstraction, thereby reducing the rate of polyunsaturated fatty acids (PUFA) oxidation. Arachidonic acid undergoes oxidation through both enzymatic and non-enzymatic mechanisms, giving rise to a ...
M. A. Fomich, A. Bekish, D. Vidović, C. Lamberson, I. Lysenko, P. Lawrence, J. Brenna, O. Sharko, V. Shmanai, M. Shchepinov   +9 more
semanticscholar   +1 more source

Eicosapentaenoic and Arachidonic Acids from Phytophthora infestans Elicit Fungitoxic Sesquiterpenes in the Potato.

Science, 1981
Mycelial extracts from Phytophthora infestans caused necrosis and elicited the accumulation of antimicrobial stress metabolites in potato tubers. A portion of the material with elicitor activity could be extracted from the mycelium by a mixture of ...
R. Bostock, J. Kuc, R. Laine
semanticscholar   +1 more source

Synthesis of isotopically labeled arachidonic acids to probe the reaction mechanism of prostaglandin H synthase.

Journal of the American Chemical Society, 2002
Prostaglandin H synthase (PGHS) catalyzes the conversion of arachidonic acid to prostaglandin G(2) in the cyclooxygenase reaction. The first step of the mechanism has been proposed to involve abstraction of the pro-S hydrogen atom from C13 to generate a ...
S. Peng, N. Okeley, A. Tsai, Gang Wu, R. Kulmacz, W. A. van der Donk   +5 more
semanticscholar   +1 more source

Prostaglandins, Arachidonic Acid, and Inflammation

Science, 1980
The enzymatic oxidation of arachidonic acid has been shown to yield potent pathological agents by two major pathways. Those of the prostaglandin (PG) pathway, particularly PGE2, have been implicated as inflammatory mediators for many years. The discovery and biological activities of thromboxane A2and prostacyclin as well as a destructive oxygen ...
Frederick A. Kuehl, Robert W. Egan
openaire   +3 more sources