Results 31 to 40 of about 71,536 (266)

Effect of angiotensin II receptor blockers on efficacy and safety of Camrelizumab plus chemotherapy in the first-line therapy for advanced non-small cell lung cancer (ARMOR I): a protocol for a prospective, real-world, multicenter, intervention clinical trial

Frontiers in Immunology
BackgroundLung cancer, particularly non-small cell lung cancer (NSCLC), remains a leading cause of cancer-related mortality worldwide. While immune checkpoint blockade (ICB), such as PD-1/PD-L1 inhibitors, have revolutionized treatment for advanced NSCLC,
Zeyu Wang, Huiyu Wang, Rui Hou, Huning Jiang, Hanfang Fan, Yuhan Zhang, Yichao Zhu, Yun Cai, Jie Mei, Junying Xu   +9 more
doaj   +1 more source

A Combined Experiment and Crystal Plasticity FEM Study of Microstructure and Texture in Aluminium Processed by Reverse and Unidirectional Accumulative Roll-Bonding

Crystals, 2019
In this report, reverse accumulative roll-bonding (ARB) was conducted for the first time. It was found that the microstructure after reverse ARB was relatively coarser than that after unidirectional ARB, and texture intensity was slightly weaker.
Hui Wang, Cheng Lu, Kiet Tieu
doaj   +1 more source

The Jurisdiction of the Advertising Regulatory Board over non-members: The Supreme Court of Appeal confirms its Herbex-order in the Bliss-matter

Potchefstroom Electronic Law Journal, 2023
This contribution seeks to answer the following question: To what extent does the Advertising Regulatory Board (ARB), as a public watchdog in the advertising industry, have the jurisdiction to consider advertising complaints filed against a person or ...
Jeanette Visagie
doaj   +1 more source

Beyond Nanoporosity: A CO2‐Conditioned Glassy Matrix Contributes to the Brittle‐to‐Ductile Transition of Nanocellular Polyetherimide

Advanced Materials, EarlyView.
The mechanical performance of nanocellular polyetherimide cannot be explained by nanoporosity alone. It is shown that CO2 saturation and desorption leave a distinct mechanical signature in the glassy matrix before foaming. This matrix contribution provides a new route to understand and optimize the brittle to ductile transition in nanocellular polymers.
Félix Lizalde‐Arroyo, Frederik Van Loock, Victoria Bernardo, Tuuli Peltola, René Bes, Alberto Tena, Miguel Ángel Rodríguez‐Pérez, Judith Martín‐de León   +7 more
wiley   +1 more source

Quantifying where human acquisition of antibiotic resistance occurs: a mathematical modelling study

BMC Medicine, 2018
Background Antibiotic-resistant bacteria (ARB) are selected by the use of antibiotics. The rational design of interventions to reduce levels of antibiotic resistance requires a greater understanding of how and where ARB are acquired.
Gwenan M. Knight, Céire Costelloe, Sarah R. Deeny, Luke S. P. Moore, Susan Hopkins, Alan P. Johnson, Julie V. Robotham, Alison H. Holmes   +7 more
doaj   +1 more source

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

Advanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao, Jun Sun, Liang Zhang, Litao Lin, Zongfeng Wan, Bingcai Pan, Sheng Tang   +6 more
wiley   +1 more source

Role of NLRP3 Inflammasome in Neurodegeneration and Cancer: A Double-Edged Sword

Onco
The innate immune system’s core sensor, the NLRP3 inflammasome (Nucleotide-binding Oligomerization Domain, Leucine-rich Repeat, and Pyrin Domain-Containing Protein 3), is a pivotal multi-protein complex that detects cellular danger and microbial threats.
Emily Do, Surajit Hansda
doaj   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Heterogeneity in Food Price Inflation Convergence Across the EU: Evidence From Club Dynamics and Structural Breaks

Agribusiness, EarlyView.
ABSTRACT This study examines food price inflation rate convergence among EU27 Member States from 2005 to 2024, focusing on structural breaks, external shocks, and regional disparities. Using panel unit root tests and club convergence analysis, the findings reveal no overall convergence but identify multiple convergence clubs.
Tibor Bareith, Imre Fertő
wiley   +1 more source

Does a Specialized Niche Market Vegetable Processor Enjoy Bargaining Power?

Agribusiness, EarlyView.
ABSTRACT Agribusiness companies may achieve competitive advantage through specialization within niche markets. One such niche is the fresh‐cut fruit and vegetable market, which has been steadily growing in Germany. This study examines whether the specialization of a German fresh‐cut producer grants it with market power within this niche market.
Nikolas Bublik, Franziska Mittag, Laura Hellstern, Sebastian Hess   +3 more
wiley   +1 more source