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Arbutin as a Skin Depigmenting Agent with Antimelanogenic and Antioxidant Properties

open access: yesAntioxidants, 2021
Arbutin is a compound of hydroquinone and D-glucose, and it has been over 30 years since there have been serious studies on the skin lightening action of this substance.
Yong Chool Boo
exaly   +3 more sources

Chemical and Biocatalytic Routes to Arbutin [PDF]

open access: yesMolecules, 2019
Arbutin (also called β-arbutin) is a natural product occurring in the leaves of a variety of different plants, the bearberries of the Ericaceae and Saxifragaceae families being prominent examples.
Hangyu Zhou   +3 more
doaj   +4 more sources

Arbutin attenuates nephrotoxicity induced by gentamicin [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2021
Objective: In this study, the impact of arbutin was examined in a gentamicin (GM)-induced nephrotoxicity model. Materials and Methods: Forty adult male Wistar rats were randomly assigned to five groups including control group; GM group, and three groups ...
Elnaz Emadi   +5 more
doaj   +3 more sources

Combination of enzyme engineering and quorum sensing system for efficient de novo biosynthesis of β-arbutin in Escherichia coli [PDF]

open access: yesSynthetic and Systems Biotechnology
β-Arbutin is a plant-derived glycoside with various biological activities, which has been applied in pharmaceuticals and whitening cosmetics. Uneven carbon flux distribution and the low catalytic efficiency of arbutin synthase limit the biosynthesis of β-
Zhuoyuan Liu   +6 more
doaj   +2 more sources

The phytochemical arbutin exerts potent anti-Toxoplasma effects through activation of cell-autonomous defense mechanisms while attenuating inflammation. [PDF]

open access: yesPLoS Neglected Tropical Diseases
BackgroundPlant-derived natural products have emerged as promising candidates for developing novel anti-toxoplasmosis drugs. This study aimed to elucidate the role and mechanism of the phytochemical arbutin in the control of T.
Zhuanzhuan Liu   +9 more
doaj   +2 more sources

Antimicrobial action of α-arbutin, β-arbutin and hydroquinone: truth and fiction

open access: yesAnnals of Mechnikov's Institute
Introduction. The leaves of lingonberry and bearberry are used in medicine for the treatment and prevention of urological infectious diseases due to the presence of diuretic and uroseptic action.
Oleksandr Maslov   +6 more
doaj   +3 more sources

Syntheses of Arbutin-.ALPHA.-glycosides and a Comparison of Their Inhibitory Effects with Those of .ALPHA.-Arbutin and Arbutin on Human Tyrosinase

open access: yesChemical and Pharmaceutical Bulletin, 2003
The effects of 4-hydroxyphenyl alpha-glucopyranoside (alpha-arbutin) and 4-hydroxyphenyl beta-glucopyranoside (arbutin) on the activity of tyrosinase from human malignant melanoma cells were examined. The inhibitory effect of alpha-arbutin on human tyrosinase was stronger than that of arbutin.
Kenji Sugimoto
exaly   +6 more sources

Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent

open access: yesMolecules, 2022
Arbutin, a hydroquinone glucoside, has been detected in ca. 50 plant families, especially in the plants of the Asteraceae, Ericaceae, Proteaceae and Rosaceae families. It is one of the most widely used natural skin-whitening agents.
Lutfun Nahar, Afaf Al-Groshi, Anil Kumar
exaly   +3 more sources

Arbutin as a potential nephroprotective agent: Dose-related effects in renal ischemia-reperfusion injury [PDF]

open access: yesBiomolecules & Biomedicine
Ischemia-reperfusion injury (IRI) presents a complex pathophysiology characterized by oxidative stress and inflammation. Arbutin, widely recognized for its use in skin whitening, also exhibits antioxidant, anti-inflammatory, and anticancer properties ...
Ferhat Sirinyildiz   +3 more
doaj   +2 more sources

Arbutin improves gut development and serum lipids via Lactobacillus intestinalis

open access: yesFrontiers in Nutrition, 2022
Arbutin has been widely studied in whitening, anti-inflammatory, and antioxidant. However, the interaction between arbutin and intestinal microbes has been rarely studied.
Jie Ma   +4 more
doaj   +1 more source

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