Results 41 to 50 of about 4,585 (174)

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Neuroprotective effects of arbutin against oxygen and glucose deprivation-induced oxidative stress and neuroinflammation in rat cortical neurons

Acta Pharmaceutica, 2022
In this study, the neuroprotective potential of arbutin (100 µmol L−1) pre-treatment and post-treatment against oxygen/ glucose deprivation (OGD) and reoxygenation (R) induced ischemic injury in cultured rat cortical neurons was explored. The OGD (60 min)
Tan Jingjing, Yadav Manoj Kumar, Devi Sushma, Kumar Manish   +3 more
doaj   +1 more source

Quantification of Arbutin in Cosmetics, Drugs and Food Supplements by Hydrophilic-Interaction Chromatography

Molecules, 2022
Arbutin, the glucoside of hydroquinone, exists in two isomers, α-arbutin and β-arbutin. The synthetic α isomer is mainly used as a skin brightening agent, while β-arbutin occurs naturally, for instance in bearberry, and is used in drugs for treatment of ...
Sarah Repert, Sandra Matthes, Wilfried Rozhon   +2 more
doaj   +1 more source

Expert Consensus on the Management of Hyperpigmentation Disorders in India: A Modified Delphi Study by the Pigmentary Disorders Society

International Journal of Dermatology, EarlyView.
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar, Sunil Dogra, Surabhi Sinha, Keshavamurthy Vinay, Indrashis Podder, Anupam Das, Bhavesh Swarnkar, B. S. Chandrashekar, Hitaishi Mehta, Madhuri Agarwal, Muthu Sendhil Kumaran, Sonali Langar, Seemal R. Desai   +12 more
wiley   +1 more source

Biological activity of leaf extract and phenolglycoside arbutin of Pyrus boissieriana Buhse

Journal of Medicinal Plants, 2004
Telka tree (Pyrus boissieriana Buhse) is growing in north forest of Iran, from beach to mountain. Peduncle, leaf and bark of some genus of Pyrus contain arbutin as phenolglycoside.
M Azadbakht, A Marston, K Hostettmann, M Ramezani, M Jahromi Moghaddam   +4 more
doaj  

Towards Bio‐Based Benzoxazines (2015–2025): A Critical Review of Renewable Building Blocks, Formaldehyde‐Free Aldehydes, and ECHA Hazard Landscape

Polymers for Advanced Technologies, Volume 37, Issue 8, August 2026.
ABSTRACT This review provides a critical overview of research on fully bio‐based benzoxazines over the period 2015–2025. A bibliometric analysis based on the Web of Science database is used to map how the field has evolved and to identify the renewable building blocks that have been most widely adopted.
Elizabeth Alvarez Perez, Alice Mija
wiley   +1 more source

Tyrosinase Inhibitors With Enhanced Potency in Mammalian and Vertebrate Models, N‐(2‐Mercaptoethyl)benzamide Derivatives: Design, Synthesis, and Evaluation

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
N‐(2‐mercaptoethyl)benzamide derivatives exhibited a much stronger tyrosinase inhibitory effect in higher organisms than in lower organisms. These derivatives exerted a much more potent anti‐melanogenic effect in zebrafish larvae and mammalian cells than in mushrooms.
Hyunhee Ju, Minchang Kim, Hyunju Lee, Hee Jin Jung, Yeonsoo Jeong, Hyejin Kang, Hyeon Seo Park, Hae Young Chung, Hyung Ryong Moon   +8 more
wiley   +1 more source

The multifaceted regulatory network of microRNA396: Orchestrating plant plasticity through coordinating development and various stresses

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 3073-3085, August 2026.
This review examines the character and function of the microRNA miR396, which helps plants balance growth, reproduction, regeneration, and survival under various stresses, highlighting recent progress and evidence that this pathway shapes crop yield, pest and disease resistance, and tissue regeneration, making it a promising target for precision crop ...
Hang Yang, Ying Yan, Lixia Zhang, Junhua Ye, Kai Wang, Zejun Hu, Lingjuan Xie, Liming Cao, Shujun Wu, Zhenying Shi   +9 more
wiley   +1 more source

Variability of the arbutin content in wild growing populations of Arctostaphylos uva-ursi (L.) Spreng from Korab Mountain, Western Balkan

Macedonian Journal of Chemistry and Chemical Engineering, 2021
Due to the presence of arbutin and hydroquinone in the bearberry plant (Arctostaphylos uva-ursi (L.) Spreng., Ericaceae), it is widely used as a urinary tract antiseptic and diuretic.
Gjoshe Stefkov, Ivana Cvetkovikj Karanfilova, Viktorija Labroska, Orhidea Krsteska, Bujar Qazimi, Marija Karapandzova, Zyber Gjoni, Nikoll Bardhi, Svetlana Kulevanova   +8 more
doaj   +1 more source

Comprehensive Phenolic Profiling and Antioxidant Evaluation of Calyx, Rind, and Edible Tissues From Non‐Astringent Persimmons (Diospyros kaki)

Chemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Tissue‐specific phenolic profiling of non‐astringent persimmons (Fuyu and Jiro) reveals substantial differences in phytochemical composition and antioxidant potential. Persimmon calyx exhibits the highest concentrations of bioactive compounds, highlighting its potential as a valuable by‐product for functional food and nutraceutical applications ...
Huiwen Wang, Muhammad Sajid Arshad, Ayesha Siddiqa, Malik Adil Nawaz, Hafiz A. R. Suleria   +4 more
wiley   +1 more source