Results 61 to 70 of about 4,532 (170)

Action of tyrosinase on alpha and beta-arbutin: A kinetic study. [PDF]

PLoS ONE, 2017
The known derivatives from hydroquinone, α and β-arbutin, are used as depigmenting agents. In this work, we demonstrate that the oxy form of tyrosinase (oxytyrosinase) hydroxylates α and β-arbutin in ortho position of the phenolic hydroxyl group, giving ...
Antonio Garcia-Jimenez, Jose Antonio Teruel-Puche, Jose Berna, José Neptuno Rodriguez-Lopez, Jose Tudela, Francisco Garcia-Canovas   +5 more
doaj   +1 more source

Arbutin Alleviates the Liver Injury of α-Naphthylisothiocyanate-induced Cholestasis Through Farnesoid X Receptor Activation

Frontiers in Cell and Developmental Biology, 2021
Cholestasis is a kind of stressful syndrome along with liver toxicity, which has been demonstrated to be related to fibrosis, cirrhosis, even cholangiocellular or hepatocellular carcinomas.
Peijie Wu, Ling Qiao, Han Yu, Hui Ming, Chao Liu, Wenjun Wu, Baixue Li   +6 more
doaj   +1 more source

Nanotechnology in Dermatology: A Comprehensive Narrative Review of Performance, Safety, and Clinical Translation

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Nanotechnology has emerged as a transformative approach in dermatology, offering potential for enhanced drug delivery, targeted therapy, and improved bioavailability for various skin conditions. However, despite significant research output, translational barriers persist due to heterogeneous study designs, safety concerns, and ...
Mohammed Saleh Al‐Dhubaibi, Ghada Farouk Mohammed, Lina Mohammed Atef, Saleh Salem Bahaj, Ahmed Mohammed Al‐Dhubaibi, Ahmad Mohammed Bukhari   +5 more
wiley   +1 more source

α-Arbutin ameliorates UVA-induced photoaging through regulation of the SIRT3/PGC-1α pathway

Frontiers in Pharmacology
Owing to its tyrosinase inhibitory activity, α-arbutin has been added to several skin care products as a skin-lightening agent. However, the protective effect of α-arbutin against ultraviolet A (UVA)-induced photoaging has not been well investigated. The
Fang Lu, Qi Zhou, Mengdi Liang, Huicong Liang, Yiwei Yu, Yang Li, Yan Zhang, Ling Lu, Yan Zheng, Jiejie Hao, Peng Shu, Peng Shu, Peng Shu, Jiankang Liu, Jiankang Liu   +14 more
doaj   +1 more source

Global consensus on the management of melanin hyperpigmentation disorders

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 760-772, May 2026.
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron, Seemal R. Desai, Marwa Abdallah, Firas Al‐Niaimi, Ncoza Dlova, Pearl E. Grimes, Jorge Ocampo‐Candiani, Rashmi Sarkar, Leihong Flora Xiang, Helio Amante Miot   +9 more
wiley   +1 more source

Lipid‐Based Nanoparticles for Time‐Release Delivery of Flavonoids

Journal of Food Process Engineering, Volume 49, Issue 5, May 2026.
Lipid‐based nanocarriers enhance the stability, bioavailability, and controlled release of flavonoids. These systems improve encapsulation efficiency and protection against degradation, highlighting their potential for food and nutraceutical applications.
Ziane da Conceição das Mercês, Viviani Ruffo de Oliveira, Simone Hickmann Flôres, Alessandro de Oliveira Rios   +3 more
wiley   +1 more source

The Effect of α-Arbutin on UVB-Induced Damage and Its Underlying Mechanism

Molecules
Ultraviolet radiation can heighten tyrosinase activity, stimulate melanocyte production, impede the metabolism of numerous melanocytes, and result in the accumulation of plaques on the skin surface.
Peng Shu, Yuan Wang, Lanyue Zhang
doaj   +1 more source

Multitargeted Modulation of Skin Dullness by HNHT Formulation: Synergistic Inhibition of Melanogenesis, Glycation, and Lipofuscin Deposition

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Skin dullness, characterized by pigmentation disorders and yellowing, is a major cosmetic concern in Asian populations. Lipofuscin exhibits ultraviolet (UV)/visible light spectral absorption, reduces skin reflectance, and contributes to dullness, whereas existing therapies targeting melanogenesis and glycation lack comprehensive ...
Zheng Wang, Yumei Fan, Peixue Ling
wiley   +1 more source

Effect of Regular Aerobic Training and Arbutin on Cardiac Total Oxidant and Antioxidant Status in Alloxan-Induced Diabetic Rat

Medical Laboratory Journal, 2015
Background and Objective: Diabetes mellitus is associated with cardiomyopathic changes, can be mediated by an oxidative stress. We aimed to study the effects of regular aerobic training and arbutin supplementation on total oxidant status (TOS) and total
M shojaee, Farzanegi, P, M habibian
doaj  

Stem Cells in Cosmetic Applications: Advancements, Challenges, and Future Directions

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Biotechnology has significantly impacted the cosmetics industry, particularly through the incorporation of plant stem cells, which possess regenerative properties beneficial for skincare. Aims This review aims to evaluate the potential benefits and challenges of using plant stem cells in cosmetics, while discussing future directions
Farid KarkonShayan, Nasim Saderi, Iman Morshedi, Behnaz Ghamari, Sepideh KarkonShayan   +4 more
wiley   +1 more source