Results 51 to 60 of about 4,585 (174)

The Effect of α-Arbutin on UVB-Induced Damage and Its Underlying Mechanism

Molecules
Ultraviolet radiation can heighten tyrosinase activity, stimulate melanocyte production, impede the metabolism of numerous melanocytes, and result in the accumulation of plaques on the skin surface.
Peng Shu, Yuan Wang, Lanyue Zhang
doaj   +1 more source

m6A‐modified DRAM1 recognized by YTHDF1 regulates autophagy during dexamethasone‐induced osteogenic inhibition

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
DRAM1 plays a critical role in the modulation of autophagy. The m6A methylation level of DRAM1 mRNA is suppressed by dexamethasone. Dexamethasone impairs autophagy‐associated osteogenic differentiation by inhibiting YTHDF1‐mediated translation of m6A‐modified DRAM1.
Ze‐Yu Lu, Peng‐Bo Chen, Qing‐Yin Xu, Muradil Mardan, Yue‐Hua Yang, Tao Liu, Wen‐Ning Xu, Huo‐Liang Zheng, Hao Cai, Hui Deng, Xing‐Xu Huang, Bo Li, Sheng‐Dan Jiang, Lei‐Sheng Jiang, Xin‐Feng Zheng   +14 more
wiley   +1 more source

Action of tyrosinase on alpha and beta-arbutin: A kinetic study. [PDF]

PLoS ONE, 2017
The known derivatives from hydroquinone, α and β-arbutin, are used as depigmenting agents. In this work, we demonstrate that the oxy form of tyrosinase (oxytyrosinase) hydroxylates α and β-arbutin in ortho position of the phenolic hydroxyl group, giving ...
Antonio Garcia-Jimenez, Jose Antonio Teruel-Puche, Jose Berna, José Neptuno Rodriguez-Lopez, Jose Tudela, Francisco Garcia-Canovas   +5 more
doaj   +1 more source

Cosmetic Enzymes as Formulation‐Integrated Actives: Mechanisms, Delivery, and Functional Evidence

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Enzymes are increasingly incorporated into cosmetic formulations as engineered bioactive components whose performance depends on stabilization, delivery, and controlled activity within complex formulation systems, rather than functioning as standalone ingredients. Aims This review examines the mechanisms of action of enzymes used in
Asmae Bouziani, Ruhan Özel, Ömer Güngör   +2 more
wiley   +1 more source

Mechanochemical Dehydrogenative Phenochalcogenazination: A Pronounced Water Effect

ChemSusChem, Volume 19, Issue 12, 26 June 2026.
We report herein the first organic solvent‐free mechanochemical dehydrogenative phenochalcogenazination reaction, with a persulfate salt as a terminal oxidant and wetted silica as a crucial additive. A mechanochemical phenochalcogenazination (X = O, S, Se) of phenols and related compounds in the ball mill is reported.
Alina Paffen, Calogero Quaranta, Kishor Gavhane, Hardik V. Mori, Frederic W. Patureau, Carsten Bolm   +5 more
wiley   +1 more source

α-Arbutin ameliorates UVA-induced photoaging through regulation of the SIRT3/PGC-1α pathway

Frontiers in Pharmacology
Owing to its tyrosinase inhibitory activity, α-arbutin has been added to several skin care products as a skin-lightening agent. However, the protective effect of α-arbutin against ultraviolet A (UVA)-induced photoaging has not been well investigated. The
Fang Lu, Qi Zhou, Mengdi Liang, Huicong Liang, Yiwei Yu, Yang Li, Yan Zhang, Ling Lu, Yan Zheng, Jiejie Hao, Peng Shu, Peng Shu, Peng Shu, Jiankang Liu, Jiankang Liu   +14 more
doaj   +1 more source

Specificity Toward Primary and Secondary Hydroxyls of Monosaccharides as Acceptor Substrates in Transphosphatidylation Catalyzed by Streptomyces sp. Phospholipase D

European Journal of Lipid Science and Technology, Volume 128, Issue 6, June 2026.
The conjugation of carbohydrates to a phospholipid backbone can be catalyzed via a transphosphatidylation reaction with phospholipase D (PLD). The illustration highlights the conjugation sites identified in this study for three common monosaccharides: glucose, fructose, and xylose.
Nikolina Barchan, Zoltan Takacs, Patrick Adlercreutz   +2 more
wiley   +1 more source

Effect of Regular Aerobic Training and Arbutin on Cardiac Total Oxidant and Antioxidant Status in Alloxan-Induced Diabetic Rat

Medical Laboratory Journal, 2015
Background and Objective: Diabetes mellitus is associated with cardiomyopathic changes, can be mediated by an oxidative stress. We aimed to study the effects of regular aerobic training and arbutin supplementation on total oxidant status (TOS) and total
M shojaee, Farzanegi, P, M habibian
doaj  

Lanzhou Lily (Lilium davidii var. unicolor) Extract Alleviates Chronic Stress–Induced Mood Disturbances by Suppressing Neuroinflammation and Modulating the Gut‐Brain Axis in Mice

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Lanzhou lily extract (LLE) alleviates chronic restraint stress–induced mood disturbances by reducing central inflammation, improving intestinal barrier integrity, attenuating systemic inflammation, and ultimately restoring gut–brain axis homeostasis in mice.
Ziyi An, Yuanyuan Xin, Yongfei Wang, Ting Wang, Junqiang Niu, Xiaogang Hu, Xiangkai Li, Weilin Jin   +7 more
wiley   +1 more source

Transcriptome Profiling Reveals Potential Genes Involved in Salicylic Acid-Induced Arbutin Synthesis in Pear

Horticulturae
Salicylic acid (SA) is known to be an efficient elicitor of secondary metabolism in plants. Arbutin, a characteristic phenolic glycoside found in ‘Yuluxiang’ pear (Pyrus bretschneideri Rehder × Pyrus sinkiangensis Yu), is widely used in lightening agents,
Junhao Li, Yuchen Ma, Tingting Cui, Shaohua Liu, Liulin Li   +4 more
doaj   +1 more source