Results 71 to 80 of about 9,193 (219)

Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytochemicals from Algerian medicinal plants were virtually screened as potential phosphodiesterase‐5 (PDE5) inhibitors for erectile dysfunction therapy. Drug‐likeness and toxicity analyses identified catechin, ellagic acid, and rosmarinic acid as safe, bioavailable candidates.
Farouk Boudou, Alaeddine Berkane, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, Brian A. Murray, Mikhael Bechelany, Ahmed Barhoum   +7 more
wiley   +1 more source

α-Arbutin ameliorates UVA-induced photoaging through regulation of the SIRT3/PGC-1α pathway

Frontiers in Pharmacology
Owing to its tyrosinase inhibitory activity, α-arbutin has been added to several skin care products as a skin-lightening agent. However, the protective effect of α-arbutin against ultraviolet A (UVA)-induced photoaging has not been well investigated. The
Fang Lu, Qi Zhou, Mengdi Liang, Huicong Liang, Yiwei Yu, Yang Li, Yan Zhang, Ling Lu, Yan Zheng, Jiejie Hao, Peng Shu, Peng Shu, Peng Shu, Jiankang Liu, Jiankang Liu   +14 more
doaj   +1 more source

Fluorescent nanoparticles for sensing

, 2020
Nanoparticle-based fluorescent sensors have emerged as a competitive alternative to small molecule sensors, due to their excellent fluorescence-based sensing capabilities.
Acosta, Alarcón-Angeles, Albertazzi, Aldewachi, Ali, Ali, Alivisatos, Amelia, Amin, Arai, Arcudi, Bae, Bagwe, Behnke, Berti, Bhattacharyya, Biteen, Bruchez, Byrappa, Cai, Cao, Carregal-Romero, Chai, Chandra, Chen, Chen, Chen, Chen, Chen, Chen, Choi, Chu, Colom, De Luca, del Mercato, del Mercato, Derr, Dhenadhayalan, Diaz-Diestra, Ding, Dmitriev, Dong, Duong, Duong, Enkin, Fehérvári, Fernández-Argüelles, Fong, Fu, Furukawa, Gao, Govindaraju, Guo, Ha, Halter, Herschel, Hines, Hornig, Hou, Hu, Huang, Huang, Huang, Iyer, Jelinek, Jeong, Jiang, Jimenez de Aberasturi, Jin, Kim, Kircher, Kong, Lakowicz, Lan, Lee, Lemon, Leobandung, Leonhardt, Lepore, Li, Li, Li, Li, Li, Li, Li, Li, Li, Li, Lim, Lin, Lin, Liu, Liu, Liu, Liu, Liu, López-Duarte, Ma, Ma, Medintz, Melnychuk, Miao, Monteiro, Naccarato, Nandi, Ng, Nie, Nooney, Ou, Pan, Pellegrino, Peng, Pompa, Potter, Qian, Qian, Qu, Rakovich, Rao, Reisch, Riccò, Riedinger, Ruedas-Rama, Saha, Samokhvalov, See, Shamirian, Shang, Shang, Shangguan, Shao, Shen, SMITH, Song, Stich, Stryer, Stöber, Su, Sun, Tang, Thiyagarajan, Toh, Ukeda, Valeur, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wei, Wen, Widengren, Wolfbeis, Wu, Wu, Wu, Wu, Wu, Xie, Xie, Xu, Xu, Yang, Yang, Ye, Yin, Yin, Yu, Yu, Yu, Zadran, Zeng, Zhang, Zhang, Zhang, Zhao, Zheng, Zhu, Zor, Zorman   +183 more
core   +1 more source

Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization

Journal of Basic Microbiology, Volume 66, Issue 2, February 2026.
ABSTRACT Monascus fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid‐lowering and multifunctional properties. To enhance MK yield in solid‐state fermentation, this study combined atmospheric and room‐temperature plasma (ARTP) mutagenesis with L‐arginine supplementation.
Chen Yang, Yang Yajing, Hong Housheng
wiley   +1 more source

The Effect of α-Arbutin on UVB-Induced Damage and Its Underlying Mechanism

Molecules
Ultraviolet radiation can heighten tyrosinase activity, stimulate melanocyte production, impede the metabolism of numerous melanocytes, and result in the accumulation of plaques on the skin surface.
Peng Shu, Yuan Wang, Lanyue Zhang
doaj   +1 more source

Uji Karakteristik Enzim Endo-Β-1,4-Glukanase, Ekso-Β-1,4-Glukanase Dan Β-Glukosidase Pada Fungi Aspergillus Niger Dan Kinetika Enzim Campuran [PDF]

, 2017
Cellulase is a group of enzymes that break down cellulose into glucose monomers obtained from endo-β-1,4-glucanase enzymes, ekso-β-1,4-glucanase and β-glucosidase produced by fungi or yeast.
, Hamid Abdillah, S.T., M.T, Karintiana, Dea   +1 more
core  

Mechanistic Role of Disulfidptosis in Type 2 Diabetes Mellitus

Molecular Nutrition &Food Research, Volume 70, Issue 4, 26 February 2026.
This study elucidates the potential link between disulfidptosis and type 2 diabetes mellitus (T2DM). We propose that high SLC7A11 expression combined with glucose starvation triggers rapid NADPH depletion and severe disulfide stress. This leads to aberrant disulfide cross‐linking of actin cytoskeletal proteins and F‐actin network collapse, inducing ...
Danqi Zou, Yanping Zou, Yujie Jin, Shilin Liu, Minghao Lin, Ruixue Deng, Zheng Nan   +6 more
wiley   +1 more source

Effect of Regular Aerobic Training and Arbutin on Cardiac Total Oxidant and Antioxidant Status in Alloxan-Induced Diabetic Rat

Medical Laboratory Journal, 2015
Background and Objective: Diabetes mellitus is associated with cardiomyopathic changes, can be mediated by an oxidative stress. We aimed to study the effects of regular aerobic training and arbutin supplementation on total oxidant status (TOS) and total
M shojaee, Farzanegi, P, M habibian
doaj  

Desenvolvimento de uma metodologia para a identificaçao de metabolitos durante o desenvolvimento do frutos de café [PDF]

, 2011
O gênero Coffea pertence à família Rubiaceae e compreende aproximadamente 100 espécies. A maioria do café comercialmente disponível consiste de grãos produzidos pelas espécies C. arabica e C. canephora.
Afonso Junior, P.C. (ed.), Bloch, Carlos J., Carvalho Andrade, Alan, Costa Alves, Gabriel Sergio, Gomes Renoldi Heimeck, Ingrid, Gomes Vieira, Natalia, Marraccini, Pierre, Pereira Freire, Luciana, Taquita, Jorge Alex, Vianna Prates, Maura, Vinecky, Felipe   +10 more
core  

Could the Biological Potency of Porcelia macrocarpa R.E. Fries (Annonaceae) be Linked to Its Diverse Metabolite Profile?

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4 ...
Fernanda Thevenard, Ivanildo A. Brito, Emerson A. Oliveira, Mariana H. Chaves, João Henrique G. Lago   +4 more
wiley   +1 more source