Results 71 to 80 of about 18,322 (139)

Exploiting bacterial effector proteins to uncover evolutionarily conserved antiviral host machinery.

PLoS Pathogens
Arboviruses are a diverse group of insect-transmitted pathogens that pose global public health challenges. Identifying evolutionarily conserved host factors that combat arbovirus replication in disparate eukaryotic hosts is important as they may tip the ...
Aaron Embry, Nina S Baggett, David B Heisler, Addison White, Maarten F de Jong, Benjamin L Kocsis, Diana R Tomchick, Neal M Alto, Don B Gammon   +8 more
doaj   +1 more source

Integrated Experimental, Chemometric, and In Silico Analyses of Larvicidal Supercritical Extracts From Myrtaceae Species Against Aedes aegypti

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The cross‐validated regression tree showed modest predictive performance. Mortality was not significantly associated with the first two PCA axes. Molecular modeling generated testable ligand–target hypotheses. Psidium cattleianum had lower LD50. The larvicidal activity of the crude extracts could not be attributed to individual constituents.
Ubiratan Alegransi Bones, Regiane Chiamente Pessetti, Gilberto Diniz Cozzer, Iuri Raiel Giacomelli, Maike Valentim Buzatto, Walter Antônio Roman Junior, Renan de Souza Rezende, Jacir Dal Magro, Vanessa da Silva Corralo   +8 more
wiley   +1 more source

α‐Glucosidase and Acetylcholinesterase (AChE) Inhibitory Activities, Larvicidal Potential and GC–MS Analysis of Endlicheria paniculata: A Combined Experimental and Molecular Docking Study

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This study investigates the essential oil composition of E. paniculata wood, bark, and leaves by GC–MS. Biological evaluations of the leaf essential oil reveal promising larvicidal potential against Aedes aegypti and in vitro inhibitory activities against α‐glucosidase and acetylcholinesterase (AChE), supported by molecular docking simulations ...
Jenifer Priscila de Araujo, Luiz Everson Da Silva, Wanderlei do Amaral, Michele Debiasi Alberton, Ana Helena Loos Moritz, Fernando Cesar Martins Betim, Deise Prehs Montrucchio, Marilis Dallarmi Miguel, Josiane de Fátima Gaspari Dias, Hélcio Silva Dos Santos, Emmanuel Silva Marinho, Márcia Machado Marinho, Jacilene Silva, Obdulio Gomes Miguel   +13 more
wiley   +1 more source

Mosquito population dynamics are shaped by interactions among larval density, temperature, and relative humidity

Ecology, Volume 107, Issue 10, October 2026.
Abstract Understanding how variation in key abiotic and biotic factors interact at ecologically relevant spatial scales is crucial for predicting population dynamics, distributions, and abundances. This is especially true for vectors that transmit human pathogens.
Nicole Solano, Emily C. Herring, Carl W. Hintz, Philip M. Newberry, Annakate M. Schatz, Joseph W. Walker, Gregory R. Jacobs, Craig W. Osenberg, Courtney C. Murdock   +8 more
wiley   +1 more source

First Phylodynamic Analysis of HRSV‐A and HRSV‐B in Rio de Janeiro, Brazil, Reveals Recurrent Dispersals From the Megalopolis Center to Suburban Cities

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Human respiratory syncytial virus (HRSV) is the leading cause of acute lower respiratory tract infections in infants and represents a major burden to public health systems worldwide. Despite its epidemiological relevance, genomic surveillance of HRSV in Brazil remains limited.
Alessandra Pavan Lamarca, Melise Chaves Silveira, Renata Campos Azevedo, Maria Angélica Arpon Marandino Guimarães, Claudia Maria Braga de Mello, Adriana Cardoso Camargo, Leandro Magalhães de Souza, Alexandra Lehmkuhl Gerber, Ana Paula C. Guimarães, Andréa Cony Cavalcanti, Ana Tereza Ribeiro Vasconcelos   +10 more
wiley   +1 more source

Enterovirus infections in children

Pediatric Investigation, Volume 10, Issue 5, Page 409-431, October 2026.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

DEET‐cyclodextrin inclusion complexes for mosquito and tick repellency: Extended repellency time and no zebrafish embryotoxicity

Pest Management Science, Volume 82, Issue 10, Page 9653-9665, October 2026.
Hydroxypropyl‐β‐cyclodextrin (HPβCD)–N,N‐diethyl‐meta‐toluamide (DEET) complex extended tick repellency to 168 h. Full protection against Aedes aegypti for 7 h with HPβCD‐DEET. HPβCD reduced DEET release and skin retention significantly. No embryotoxicity observed below 325 mg L−1 in zebrafish model.
Gessyka Rayana Silva Pereira, Gleidson Cardoso, Maria Luiza Kuhn Camargo, Michele Resende Machado, Mayara Macedo Barrozo, Juscelino Rodrigues, Gisele Augusto Rodrigues de Oliveira, Caio Monteiro, Christian Luz, Ricardo Neves Marreto, Stephânia Fleury Taveira   +10 more
wiley   +1 more source

Arbovirus Epidemics as Global Health Imperative, Africa, 2023

Emerging Infectious Diseases
Arboviruses represent a major cause of illness in Africa and have the potential to trigger widespread epidemics. We present data on arbovirus epidemics in Africa in 2023 and demonstrate the need for global public health authorities to intensify efforts ...
Salifou T. Bangoura, Alpha-Kabinet Keita, Maladho Diaby, Sidikiba Sidibé, Frederic Le-Marcis, Saidouba C. Camara, Stéphanie Maltais, Kadio J.J.O. Kadio, Eric D’Ortenzio, Alioune Camara, Eric Delaporte, Alexandre Delamou, Philippe Vanhems, Michèle Ottmann, Nagham Khanafer, Abdoulaye Touré   +15 more
doaj   +1 more source

Thiazolidine‐2,4‐dione and Thiazole Derivatives as Privileged Structures for Dengue Virus: A Review of Medicinal Chemistry Aspects

ChemistrySelect, Volume 11, Issue 37, 6 October 2026.
This graphical abstract summarizes thiazole, thiazolidine‐2,4‐dione, and hybrid compounds investigated as antiviral candidates against dengue virus. Representative structures and reported potencies are presented in the context of DENV serotypes. Proposed molecular targets include NS2B–NS3 protease and NS5.
Pedro César de Souza, Thaynara Paula Warren Bezerra, Matheus Vinicius Guimarães de Melo, Thayná da Silva Barros, Matheus Italo da Conceição, Michelle Melgarejo da Rosa, Moacyr Jesus Barreto de Melo Rêgo   +6 more
wiley   +1 more source

Assessing the Use of Oxford Nanopore Technologies Sequencing for Detection of Stable Wolbachia Bacterial Strain in Symbiosis in Wild Anopheles Mosquitoes From the WHO African Region

Environmental Microbiology, Volume 28, Issue 10, October 2026.
This study assesses Oxford Nanopore Technology sequencing to detect Wolbachia in Anopheles mosquitoes. To do this, samples were analysed using the ONT field sequencing kit and sequenced using a minION flow cell and the ONT 16S barcoding kit and Rapid barcoding kit sequenced using Flongle flow cells.
Laura Chatterley, Nicola Hull, Isabel Hughes, Seynabou Sougoufara, Owain Meek, Murat Ceyran, Vishaal Dhokiya, Janvier Bandibabone, Cyprian Adala, Elin Cunningham, Shehu Shagari Awandu, Helene Kaminski‐Nenkam, Antonio Nkondjio, Grant L. Hughes, Eva Heinz, Thomas Walker   +15 more
wiley   +1 more source