Results 31 to 40 of about 13,713 (174)

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

Costs of hospital admissions due to COVID-19 in the federal capital of Brazil: a study based on hospital admission authorizations

Brazilian Journal of Infectious Diseases
This is a cost analysis study based on hospital admissions, conducted from the perspective of the Brazilian Unified Health System (SUS), carried out in a cohort of patients hospitalized at the University Hospital of Brasília (UHB) due to Severe Acute ...
Ana Carolina Esteves da Silva Pereira, Luciana G. Gallo, Ana Flávia de M. Oliveira, Maria Regina F. de Oliveira, Henry M. Peixoto   +4 more
doaj   +1 more source

Exposure of Egyptian Rousette Bats (Rousettus aegyptiacus) and a Little Free-Tailed Bat (Chaerephon pumilus) to Alphaviruses in Uganda

Diseases, 2022
The reservoir for zoonotic o’nyong-nyong virus (ONNV) has remained unknown since this virus was first recognized in Uganda in 1959. Building on existing evidence for mosquito blood-feeding on various frugivorous bat species in Uganda, and seroprevalence ...
Rebekah C. Kading, Erin M. Borland, Eric C. Mossel, Teddy Nakayiki, Betty Nalikka, Jeremy P. Ledermann, Mary B. Crabtree, Nicholas A. Panella, Luke Nyakarahuka, Amy T. Gilbert, Julian C. Kerbis-Peterhans, Jonathan S. Towner, Brian R. Amman, Tara K. Sealy, Barry R. Miller, Julius J. Lutwama, Robert M. Kityo, Ann M. Powers   +17 more
doaj   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Changes in the Transmission Dynamic of Chikungunya Virus in Southeastern Senegal

Viruses, 2020
In Senegal, chikungunya virus (CHIKV) is maintained in a sylvatic cycle and causes sporadic cases or small outbreaks in rural areas. However, little is known about the influence of the environment on its transmission.
Abdourahmane Sow, Birgit Nikolay, Oumar Faye, Simon Cauchemez, Jorge Cano, Mawlouth Diallo, Ousmane Faye, Bakary Sadio, Oumar Ndiaye, Scott C. Weaver, Anta T. Dia, Amadou Alpha Sall, Denis Malvy   +12 more
doaj   +1 more source

Surveillance of the major pathogenic arboviruses of public health concern in Gabon, Central Africa: increased risk of West Nile virus and dengue virus infections

BMC Infectious Diseases, 2021
Background Increasing arbovirus infections have been a global burden in recent decades. Many countries have experienced the periodic emergence of arbovirus diseases. However, information on the prevalence of arboviruses is largely unknown or infrequently
Yuri Ushijima, Haruka Abe, Georgelin Nguema Ondo, Rodrigue Bikangui, Marguerite Massinga Loembé, Vahid R. Zadeh, Joseph G. E. Essimengane, Armel V. N. Mbouna, Emmanuel B. Bache, Selidji T. Agnandji, Bertrand Lell, Jiro Yasuda   +11 more
doaj   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Economic Impact of Dengue Virus in Mexico Over One Decade: A Systematic Literature Review (2010–2020)

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Background Dengue is a major mosquito‐borne viral disease worldwide, imposing significant healthcare burden on governments in countries where it is endemic, such as Mexico. This systematic review focused on studies reporting the cost of dengue in Mexico during 2010–2020.
Gilberto Sánchez‐González, Luz del C. Hernández‐Hernández, Elaine Gallagher   +2 more
wiley   +1 more source

Arbovirus infections incidence in the south of the European part of the Russian Federation

Журнал микробиологии, эпидемиологии и иммунобиологии, 2021
Purpose: analysis of the arbovirus infections incidence in the south of the European part of the Russian Federation in 2015–2019.Materials and methods.
N. F. Vasilenko, D. A. Prislegina, O. V. Maletskaya, T. V. Taran, A. E. Platonov, A. N. Kulichenko   +5 more
doaj   +1 more source

Postinfection therapy of arbovirus infections in mice [PDF]

Antimicrobial Agents and Chemotherapy, 1989
Most antiviral agents are efficacious prophylactically in vivo, and a few are efficacious for postinfection (p.i.) therapy. To explore possibilities for p.i. therapy of encephalogenic Banzi virus (BZV) and Semliki Forest virus infections in mice, we evaluated candidate antiviral therapies after development of the first clinical signs of infection.
I P, Singh, D H, Coppenhaver, M, Sarzotti, P, Sriyuktasuth, J, Poast, H B, Levy, S, Baron   +6 more
openaire   +2 more sources