Results 31 to 40 of about 1,653 (173)
The recent discovery of a carotenoid light-harvesting antenna in xanthorhodopsin, a retinal-based proton pump in Salinibacter ruber, made use of photoinhibition of respiration in whole cells to obtain action spectra [Balashov et al. Science 309, (2005) 2061-2064].
Vladimir A. Boichenko +4 more
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Effects of Triton X-100 on Proton Transfer and in the Photocycle of Archaerhodopsin 4 [PDF]
Archaerhodopsin 4 (AR4), a retinal-containing membrane protein, exhibits a reversed order of proton release and uptake at neutral pH, as compared to the well-known bacteriorhodopsin (BR). In a preceding report, we stated that Triton X-100 solubilized the claret membrane containing AR4 (CM) into monomeric proteins and altered the time order in AR4 at ...
Yazhuo Wang +4 more
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Summary Optogenetics, the regulation of proteins by light, has revolutionized the study of excitable cells, and generated strong interest in the therapeutic potential of this technology for regulating action potentials in neural and muscle cells. However,
Dany Spencer Adams +2 more
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Optogenetic modulation of peripheral nociceptive neurons with biocompatible optoelectronic implants [PDF]
Hyperexcitability of peripheral sensory neurons plays a critical role in the development and maintenance of chronic pain. Pharmacological analgesics used in clinics reduce neuronal activity. They often come with non‐negligible side effects.
Paul Chu Sin Chung +9 more
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A tubular assembly of archaerhodopsin
Hisashi Okumura +5 more
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Bacteriorhodopsin of purple membrane reverses anisotropy outside the pH range of proton pumping based on logic gate realization [PDF]
The bacteriorhodopsin of purple membrane is the first discovered light-sensing protein among ion transporting microbial rhodopsins, some of which (e.g.
Hamdy I. A. Mostafa, Abdo A. Elfiki
doaj +2 more sources
Spectral tuning of Archaerhodopsin 3 in Escherichia coli
Microbial rhodopsins are proteins that act as light driven proton pumps located in the plasma membrane of eukarya, bacteria and archaea. These proteins facilitate the movement of protons by light-induced isomerisation of a central retinal chromophore found in the transmembrane core of the opsin protein.
Owen Crowther
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Orexin/hypocretin neurons have a crucial role in the regulation of sleep and wakefulness. Recent optogenetic studies revealed that the activation or inhibition of orexin neuronal activity affects the probability of sleep/wakefulness transition in the acute phase.
Tomomi Tsunematsu +5 more
semanticscholar +5 more sources
A versatile approach to high-density microcrystals in lipidic cubic phase for room-temperature serial crystallography. [PDF]
A versatile approach for the preparation of high‐density membrane protein microcrystals in lipidic cubic phase for serial crystallography is described.Serial crystallography has emerged as an important tool for structural studies of integral membrane proteins.
Birch J +20 more
europepmc +2 more sources
Central terminals of primary afferents coordinate the spontaneous activity of dorsal horn neurons. [PDF]
Abstract figure legend Primary afferents transmit sensory information to second‐order neurons in the spinal cord, but also receive presynaptic contacts regulating synaptic transmission. Opto‐ and chemogenetic modulation of the excitability of primary afferent terminals reveals its fundamental role in synchronising spontaneous activity of dorsal horn ...
Lucas-Romero J +2 more
europepmc +2 more sources

