A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing [PDF]
We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers ...
Berenyi, Antal +21 more
core +3 more sources
Abstract Objective For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibition of the SNr produces robust seizure suppression in a range of seizure models.
Devin Palmer, Patrick A. Forcelli
wiley +1 more source
Exploring adult hippocampal neurogenesis using optogenetics [PDF]
In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core
Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin [PDF]
We developed a technique, “flash memory”, to record a photochemical imprint of the activity state—firing or not firing—of a neuron at a user-selected moment in time. The key element is an engineered microbial rhodopsin protein with three states.
Brinks, Daan +5 more
core +2 more sources
Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex
Abstract figure legend Many studies of cortical circuits use optogenetic activation of inhibitory interneurons to suppress pyramidal cell activity, but after the light is turned off pyramidal cells sometimes show excess spiking, which is called a post‐inhibitory rebound.
Jared T. Shapiro +2 more
wiley +1 more source
Origin of fluorescence and voltage sensitivity in microbial rhodopsin-based voltage sensors [PDF]
QuasArs, eine neue Klasse von fluoreszierenden Membranspannungssensoren basierend auf Archaerhodopsin-3, wurde von Hochbaum et al. im Jahr 2014 beschrieben.
Silapetere, Arita
core +1 more source
Central Amygdala Somatostatin Neurons Gate Passive and Active Defensive Behaviors [PDF]
The central amygdala (CeA) has a key role in learning and expression of defensive responses. Recent studies indicate that somatostatin-expressing (SOM(+)) neurons in the lateral division of the CeA (CeL) are essential for the acquisition and recall of ...
Albeanu, D. F. +3 more
core +1 more source
Optogenetic Pacing: Current Insights and Future Potential
Airong Li, Rudolph E Tanzi Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USACorrespondence: Airong Li; Rudolph E TanziGenetics and Aging Research Unit, Department of
Li A, Tanzi RE
doaj
Optogenetic feedback control of neural activity [PDF]
Optogenetic techniques enable precise excitation and inhibition of firing in specified neuronal populations and artifact-free recording of firing activity.
Ahrens +54 more
core +2 more sources
Output from VIP cells of the mammalian central clock regulates daily physiological rhythms [PDF]
The suprachiasmatic nucleus (SCN) circadian clock is critical for optimising daily cycles in mammalian physiology and behaviour. The roles of the various SCN cell types in communicating timing information to downstream physiological systems remain ...
A Kalsbeek +70 more
core +1 more source

