Results 61 to 70 of about 2,147 (170)

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing [PDF]

open access: yes, 2011
We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers ...
Berenyi, Antal   +21 more
core   +3 more sources

Restoring failed inhibition in the substantia nigra pars reticulata suppresses absence seizures in rats

open access: yesEpilepsia, EarlyView.
Abstract Objective For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibition of the SNr produces robust seizure suppression in a range of seizure models.
Devin Palmer, Patrick A. Forcelli
wiley   +1 more source

Exploring adult hippocampal neurogenesis using optogenetics [PDF]

open access: yes, 2018
In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core  

Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin [PDF]

open access: yes, 2015
We developed a technique, “flash memory”, to record a photochemical imprint of the activity state—firing or not firing—of a neuron at a user-selected moment in time. The key element is an engineered microbial rhodopsin protein with three states.
Brinks, Daan   +5 more
core   +2 more sources

Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex

open access: yesThe Journal of Physiology, Volume 603, Issue 16, Page 4609-4636, 15 August 2025.
Abstract figure legend Many studies of cortical circuits use optogenetic activation of inhibitory interneurons to suppress pyramidal cell activity, but after the light is turned off pyramidal cells sometimes show excess spiking, which is called a post‐inhibitory rebound.
Jared T. Shapiro   +2 more
wiley   +1 more source

Origin of fluorescence and voltage sensitivity in microbial rhodopsin-based voltage sensors [PDF]

open access: yes, 2022
QuasArs, eine neue Klasse von fluoreszierenden Membranspannungssensoren basierend auf Archaerhodopsin-3, wurde von Hochbaum et al. im Jahr 2014 beschrieben.
Silapetere, Arita
core   +1 more source

Central Amygdala Somatostatin Neurons Gate Passive and Active Defensive Behaviors [PDF]

open access: yes, 2016
The central amygdala (CeA) has a key role in learning and expression of defensive responses. Recent studies indicate that somatostatin-expressing (SOM(+)) neurons in the lateral division of the CeA (CeL) are essential for the acquisition and recall of ...
Albeanu, D. F.   +3 more
core   +1 more source

Optogenetic Pacing: Current Insights and Future Potential

open access: yesResearch Reports in Clinical Cardiology, 2020
Airong Li, Rudolph E Tanzi Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USACorrespondence: Airong Li; Rudolph E TanziGenetics and Aging Research Unit, Department of
Li A, Tanzi RE
doaj  

Optogenetic feedback control of neural activity [PDF]

open access: yes, 2015
Optogenetic techniques enable precise excitation and inhibition of firing in specified neuronal populations and artifact-free recording of firing activity.
Ahrens   +54 more
core   +2 more sources

Output from VIP cells of the mammalian central clock regulates daily physiological rhythms [PDF]

open access: yes, 2020
The suprachiasmatic nucleus (SCN) circadian clock is critical for optimising daily cycles in mammalian physiology and behaviour. The roles of the various SCN cell types in communicating timing information to downstream physiological systems remain ...
A Kalsbeek   +70 more
core   +1 more source

Home - About - Disclaimer - Privacy