Results 71 to 80 of about 2,147 (170)
Background: Intracellular acidosis in the ischemic penumbra can contribute to further cell death, effectively enlarging the infarct core. Restoring the acid-base balance may enhance tissue survivability after cerebral ischemia.
Bin Bo +4 more
doaj +1 more source
Visualization of myelin‐forming oligodendrocytes in the adult mouse brain
Single‐cell RNA sequence data subdivided oligodendrocyte differentiation steps into newly formed oligodendrocytes (NFOLs), myelin‐forming oligodendrocytes (MFOLs), and mature oligodendrocytes (MOLs). We focused on NFOL‐specific RNA, long non‐coding oligodendrocyte 1 (LncOL1) and generated an LncOL1‐tTA mouse line.
Kiichi Yokoyama +3 more
wiley +1 more source
Cortical Interneurons Differentially Shape Frequency Tuning following Adaptation
Summary: Neuronal stimulus selectivity is shaped by feedforward and recurrent excitatory-inhibitory interactions. In the auditory cortex (AC), parvalbumin- (PV) and somatostatin-positive (SOM) inhibitory interneurons differentially modulate frequency ...
Ryan G. Natan +2 more
doaj +1 more source
Bioelectronic Implantable Devices for Physiological Signal Recording and Closed‐Loop Neuromodulation
This review explores bioelectronic implantable devices, which monitor physiological signals and detect diseases early by interfacing with bodily organs. It highlights their use in neuromodulation for precise therapeutic delivery and discusses closed‐loop systems that adapt treatments from real‐time feedback.
Saehyuck Oh +6 more
wiley +1 more source
Optogenetics provide a potential alternative approach to the treatment of chronic pain, in which complex pathology often hampers efficacy of standard pharmacological approaches.
Philipp Mayer +14 more
doaj +1 more source
Initial photophysical characterization of the proteorhodopsin optical proton sensor (PROPS) [PDF]
Fluorescence is not frequently used as a tool for investigating the photocycles of rhodopsins, largely because of the low quantum yield of the retinal chromophore.
Nadeau, Jay L.
core +2 more sources
Different dendritic domains of the GnRH neuron underlie the pulse and surge modes of GnRH secretion in female mice [PDF]
The gonadotropin-releasing hormone (GnRH) neurons exhibit pulse and surge modes of activity to control fertility. They also exhibit an unusual bipolar morphology comprised of a classical soma-proximal dendritic zone and an elongated secretory process ...
core +3 more sources
Dopaminergic Neurons in Zona Incerta Drives Appetitive Self‐Grooming
Dopaminergic neurons in the zona incerta (A13) integrate sensory information and drive self‐grooming and place preference by releasing dopamine to the periaqueductal gray (PAG). The dependency of place preference on self‐grooming suggests that self‐grooming is appetitive.
Zhiying Jiang +8 more
wiley +1 more source
Our manuscript describes the crucial role of the peripheral nervous system in health, underscoring the therapeutic potential of neuromodulation for a range of serious medical conditions. In this comprehensive review, we explore various neuromodulation techniques—such as electrical, chemical, optical, and mechanical stimulation—that have been enhanced ...
Hayoung Song +9 more
wiley +1 more source
Controlling Interneuron Activity in Caenorhabditis Elegans to Evoke Chemotactic Behaviour [PDF]
Animals locate and track chemoattractive gradients in the environment to find food. With its small nervous system, Caenorhabditis elegans is a good model system in which to understand how the dynamics of neural activity control this search behaviour ...
Guo, Zengcai V. +3 more
core +1 more source

