Results 51 to 60 of about 106,645 (270)

Archetypal Analysis and Structured Sparse Representation for Hyperspectral Anomaly Detection

Remote Sensing, 2021
Hyperspectral images (HSIs) often contain pixels with mixed spectra, which makes it difficult to accurately separate the background signal from the anomaly target signal.
Genping Zhao, Fei Li, Xiuwei Zhang, Kati Laakso, Jonathan Cheung-Wai Chan   +4 more
doaj   +1 more source

Probabilistic Archetypal Analysis [PDF]

, 2014
Archetypal analysis represents a set of observations as convex combinations of pure patterns, or archetypes. The original geometric formulation of finding archetypes by approximating the convex hull of the observations assumes them to be real valued ...
Eugster, Manuel J. A., Seth, Sohan
core  

Consensus mutagenesis reveals that non-helical regions influence thermal stability of horseradish peroxidase [PDF]

, 2008
The enzyme horseradish peroxidase has many uses in biotechnology but a stabilized derivative would have even wider applicability. To enhance thermal stability, we applied consensus mutagenesis (used successfully with other proteins) to recombinant ...
Amin, Arnold, Azevedo, Barry J. Ryan, Bonnaffe, Carlsson, Ciarán Ó'Fágáin, Dunford, Duroux, Eijsink, Eremin, Fishman, Flores, French, Gajhede, Garcia, Gonera, Grigorenko, Ignatenko, Kamal, Kamal, Kuhlmeyer, Lehmann, Lehmann, Lei, Lesk, Lin, Lipovsek, Liu, Magliery, Maniatis, Mary J. O'Connell, McEldoon, Miland, Miland, Miyazaki, Morawski, Nielsen, O'Brien, O'Brien, Pina, Ryan, Ryan, Ryan, Ryan, Ryan, Smith, Steipe, Tams, Thompson, van den Burg, Veitch, Wang, Watanabe, Welinder, Yang, Yang   +56 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

A data-driven classification of 3D foot types by archetypal shapes based on landmarks.

PLoS ONE, 2020
The taxonomy of foot shapes or other parts of the body is important, especially for design purposes. We propose a methodology based on archetypoid analysis (ADA) that overcomes the weaknesses of previous methodologies used to establish typologies. ADA is
Aleix Alcacer, Irene Epifanio, M Victoria Ibáñez, Amelia Simó, Alfredo Ballester   +4 more
doaj   +1 more source

Archetypal analysis of galaxy spectra [PDF]

Monthly Notices of the Royal Astronomical Society, 2003
6 pages, 5 figures, 1 style-file.
Chan, B, Mitchell, Daniel A, Cram, Lawrence   +2 more
openaire   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Classical Elements of Nature in Galway Kinnell’s The Book of Nightmares

Revista Espiga, 2020
The aim of this study is to analyze Kinnell’s The Book of Nightmares from an archetypal and mythological approach. While there have been different approaches to reading Kinnell’s book-length poem, their primary concern has been Kinnell’s work in ...
Elizabeth Quirós-García
doaj   +3 more sources

Inferring End‐Members From Geoscience Data Using Simplex Projected Gradient Descent‐Archetypal Analysis

Journal of Geophysical Research: Machine Learning and Computation
End‐member mixing analysis (EMMA) is widely used to analyze geoscience data for their end‐members and mixing proportions. Many traditional EMMA methods depend on known end‐members, which are sometimes uncertain or unknown. Unsupervised EMMA methods infer
Zanchenling Wang, Tao Wen
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source