Results 61 to 70 of about 22,053,960 (269)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

The Mythical Analysis of the Great War in the Illustrations of Shamloo’s Shahnama, The Illustrated Epic of Kings Based on Northrop Frye’s Archetypal Approach [PDF]

هنر و تمدن شرق
The art of any nation is deeply rooted in the beliefs, ideology, and mythology of its people, and decoding it requires knowledge of their myths. Mythical criticism is an interdisciplinary approach that deals with the interpretation of a literary work and
Sanaz Asadi, Nadia Maghuly
doaj   +1 more source

Classical Elements of Nature in Galway Kinnell’s The Book of Nightmares

Revista Espiga, 2020
The aim of this study is to analyze Kinnell’s The Book of Nightmares from an archetypal and mythological approach. While there have been different approaches to reading Kinnell’s book-length poem, their primary concern has been Kinnell’s work in ...
Elizabeth Quirós - García
doaj   +3 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A framework for evaluating regional hydrologic sensitivity to climate change using archetypal watershed modeling [PDF]

Hydrology and Earth System Sciences, 2013
The current study focuses on the development of a regional framework to evaluate hydrologic and sediment sensitivity, at various stages of urban development, due to predicted future climate variability.
S. R. Lopez, T. S. Hogue, E. D. Stein
doaj   +1 more source

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos, Morgan C. Devore, Christina Lam, Courtney Park, Sanjay Bidichandani, David R. Lynch   +5 more
wiley   +1 more source

ARCHETYPAL ANALYSIS OF STOCHASTIC TEXTS: A DIALOGICAL HUMAN-ALGORITHMIC APPROACH [PDF]

Psicologia & Sociedade
After the GPT-3 boom, there is an ongoing debate regarding the language heuristics in automatic text generation, as well as their usefulness for scientific inquiry.
Gustavo Mendonça Ferratti, Sérgio Ricardo Perassoli Jr., Silvio Eduardo Alvarez Candido, Mario Sacomano Neto, Aparecido Donizete Rossi   +4 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Unveiling agroecological transitions in Northern Patagonia: a comparative typology approach

Frontiers in Agronomy
IntroductionAgroecological transitions are complex, multidimensional processes that require analytical tools capable of capturing contextual and systemic diversity. Typology construction has proven valuable for characterizing the heterogeneity of farming
Valeria Esther Álvarez, Valeria Esther Álvarez, Verónica Andrea El Mujtar, Andrea Gabriela Cardozo, Andrea Gabriela Cardozo, Leandro Áxel Sisón Cáceres, Leila Yamila Heinzle, Elisa Castán, Pablo Adrián Tittonell, Pablo Adrián Tittonell, Pablo Adrián Tittonell   +10 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source