Results 51 to 60 of about 124,672 (293)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Verifying the Feasibility of Implementing Semantic Interoperability in Different Countries Based on the OpenEHR Approach: Comparative Study of Acute Coronary Syndrome Registries

open access: yesJMIR Medical Informatics, 2021
BackgroundThe semantic interoperability of health care information has been a critical challenge in medical informatics and has influenced the integration, sharing, analysis, and use of medical big data.
Lingtong Min   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Global low carbon transitions in the power sector: A machine learning clustering approach using archetypes

open access: yesJournal of Economy and Technology
This study presents an archetype-based approach to designing effective strategies for low-carbon transitions in the power sector. To achieve global energy transition goals, a renewable energy transition is critical, and understanding diverse energy ...
Abdullah Alotaiq
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Information architecture for a federated health record server [PDF]

open access: yes, 2002
This paper describes the information models that have been used to implement a federated health record server and to deploy it in a live clinical setting.
Austin, T   +5 more
core  

Архетип и его именование в художественной словесности

open access: yesPolilog: Studia Neofilologiczne, 2012
Name and archetype: towards an essence of the artistic creativity This article is devoted to a problem of the archetype in the context of the theory of name. This aspect has not been distinctly outlined in the philological thought yet.
Alla Bolszakowa
doaj  

Archetypes and design [PDF]

open access: yesSHS Web of Conferences, 2019
Identification of basic archetypes and their remote structure in the context of civilization design, industrial and communicative design makes it possible to specify age-long stability of certain patterns and instruments.
Pigulevskiy Viktor, Mirskaya Liudmila
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Electronic health record standards [PDF]

open access: yes, 2006
Objectives: This paper seeks to provide an overview of the initiatives that are proceeding internationally to develop standards for the exchange of electronic health record (EHR) information between EHR systems.Methods: The paper reviews the clinical and
Kalra, D
core   +1 more source

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