Results 111 to 120 of about 19,172 (304)

Improved Swedish Accessibility Hindered by a Housing Imbroglio

open access: yes, 2016
The quest to make Sweden accessible for all has a long tradition. Stemming from initiatives of charitable organisations in the early 20th century, accessibility became a physical requirement through the Swedish building act of the 1960s.
Andersson, Jonas E.
core  

YOLOv11-Safe: An Explainable AI Framework for Data-Driven Building Safety Evaluation and Design Optimization in University Campuses

open access: yesBuildings
Campus buildings often present hidden safety risks such as falls and wheelchair instabilities, which are closely related to architectural layout, material selection, and accessibility design.
Jing Hou   +5 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

“True” Accessibility Barriers of Heritage Buildings

open access: yes
Heritage buildings, which symbolize the pride of a nation, were built prior to the development of current standards, including those for accessibility. As nations strive for equity, diversity, and inclusion, creating barrier-free environments, including ...
Samir E. Chidiac, Mouna A. Reda
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Vertical Mobility: a multi-faceted Tool for enhancing Architectural Heritage

open access: yes, 2020
Vertical mobility plays a key role in the accessibility of architectural heritage: an ex- traneous requisite, but indispensable for enhancing the built heritage in an inclusive way. In this framework, in the light of their multiple technological features,
TRAPANI, Ferdinando   +3 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Architecture for environmental data access in WSN

open access: yes, 2011
This paper shows different issues found in the real implementation of either a WSN or its data exploitation system for an environmental monitoring application. A generic software architecture for interfacing both is proposed and tested on a real case.
Mora-Merchán, Javier María   +5 more
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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