Results 61 to 70 of about 2,883,041 (303)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Style-Based architectural reconfigurations [PDF]

open access: yes, 2007
We introduce Architectural Design Rewriting (ADR), an approach to the design of reconfigurable software architectures whose key features are: (i) rule-based approach (over graphs); (ii) hierarchical design; (iii) algebraic presentation; and (iv ...
Lluch-Lafuente, Alberto   +7 more
core   +1 more source

Resilience and urban form transformation: from San Fulgencio monastery to market in Écija, Spain

open access: yesCity, Territory and Architecture, 2023
The nineteenth century city in Spain is defined by modernisation, transformation and urban renewal. The production of urban plans played an important role in projects for the realignment of streets and the opening of new roads.
F.-Javier Ostos-Prieto   +2 more
doaj   +1 more source

Polvese Chapels. The Sense of the Sacred in Nine Offline Places

open access: yesIn_Bo, 2022
The concept of the sacred can be perhaps broadened by comparing it with its opposite, revealing new meanings. If the term profane etymologically refers to the need to “stand outside the temple” (from the Latin pro-fanus, literally “in front of the temple”
Paolo Belardi   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

THE ACADEMY OF FINE ARTS GARDEN IN THE SYSTEM OF ACADEMIC QUARTER PUBLIC SPACES: CHAPTERS OF HISTORY AND DEVELOPMENT PROSPECTS

open access: yesАрхитектон, 2022
The article presents the first ever analysis of the Academic Garden as part of the system of public spaces in the Academy of Fine Arts quarter. The role of the Academic Garden in the visual and spatial perception of the architectural composition of the ...
Vasilenko Andrey I.
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Architectural year book, University of Illinois. 1 [PDF]

open access: yes, 1911
None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...

core   +1 more source

Policy Architectures for Compositional Generalization in Control

open access: yesCoRR, 2022
Many tasks in control, robotics, and planning can be specified using desired goal configurations for various entities in the environment. Learning goal-conditioned policies is a natural paradigm to solve such tasks. However, current approaches struggle to learn and generalize as task complexity increases, such as variations in number of environment ...
Allan Zhou   +3 more
openaire   +4 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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