Results 61 to 70 of about 720,601 (301)

Architectural design education: in varietate unitas [PDF]

International Journal of Technology and Design Education, 2017
A fascinating and rich landscape of personal views and approaches can be seen in architectural design and in architectural design education. This variation may be confusing for students. This paper focuses on the question: is the framework of generic elements that we developed for explicating the design process helpful to compare the differences in ...
van Dooren, E.J.G.C. (author), van Merriënboer, J. (author), Boshuizen, H.P.A. (author), van Dorst, M.J. (author), Asselbergs, M.F. (author)   +4 more
openaire   +5 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Assessment for learning in architectural design programmes [PDF]

, 2008
This paper compares the learning and teaching strategies practised in the programmes of the Architectural Subject Group at the University of Northumbria with best practices of assessment (‘Assessment for Learning’) as promoted by the Centre for ...
Holgate, Peter
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Modelling process knowledge in architectural design: A case-based approach [PDF]

, 1995
The paper presents on-going research aimed at the understanding and support of process knowledge in architectural design, from early and not sufficiently defined, to satisfactorily-defined phases.
Arlati, Ezio, Bottelli, Valeria, Fogh, Christian, Tirassa, Maurizio   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Case analysis and design logic framework of eco-environment-oriented development (EOD) in China

Journal of Asian Architecture and Building Engineering
As China undergoes a strategic shift from a growth-centric development paradigm to one that prioritizes environmental sustainability, the Eco-Environment-Oriented Development (EOD) model has emerged as a policy innovation and is currently being ...
Lu Li, Le Luo, Yang Qu, Mao Han
doaj   +1 more source

Increasing information feed in the process of structural steel design [PDF]

, 2011
Research initiatives throughout history have shown how a designer typically makes associations and references to a vast amount of knowledge based on experiences to make decisions.
De Meyer, Ronald, Jonckheere, Tine, Pauwels, Pieter, Van Campenhout, Jan   +3 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Houses in Malaysia: Fusion of the east and the west [PDF]

, 2005
A great number of architectural scholars in Malaysia learned about western architecture to be used as precedent studies in their design. Few realized that part of the origin of the modern western architecture was actually from the east.
Wan Ismail, Wan Hashimah
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