Results 81 to 90 of about 145,790 (269)

Spatial patterns of Geological Culture Villages (Towns) and their influential factors in China

Heritage Science
Geological Culture Villages Towns (GCV(T)s) serve as rich repositories of geological resources, embodying significant historical and cultural values that mirror the dynamic interplay between Earth's evolution and human societies. Despite their importance,
Yunxing Zhang, Zhenyu Zhang, Chenchen Lu, Meiyu Yang, Zhengyu Zhao, Cuihua Gu   +5 more
doaj   +1 more source

Ground-Motion Intensity Measures for the Seismic Response of the Roof-Isolated Large-Span Structure

Buildings
Ground-motion intensity measures (IMs), which quantify and describe the characteristics of earthquake ground motion, are of utmost importance in the assessment of seismic risk and the design of resilient structures with large spans.
Wei Zhen, Yikun Qiu, Yanhua Zhang, Wei Li   +3 more
doaj   +1 more source

Architectural design rewriting as an architecture description language

, 2008
Architectural Design Rewriting (ADR) is a declarative rule-based approach for the design of dynamic software architectures. The key features that make ADR a suitable and expressive framework are the algebraic presentation of graph-based structures and ...
Lluch-Lafuente, Alberto, Bruni, Roberto, Tuosto, Emilio, Montanari, Ugo   +3 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Analysis of the current state of the compositional ensemble of Yerevan's central square: challenges and proposed solutions

Budownictwo i Architektura
This article explores contemporary challenges related to the spatial environment of public squares, focusing specifically on the architectural ensemble of Yerevan’s Republic Square.
Zhora Sagaryan, Karen Azatyan
doaj   +1 more source

Architectural authorship in generative design

, 2007
The emergence of evolutionary digital design methods, relying on the creative generation of novel forms, has transformed the design process altogether and consequently the role of the architect.
Theodoropoulou, A.
core  

PLM and architectural rehabilitation : a framework to improve collaboration in the early stages of design [PDF]

, 2012
Recent evolutions in French law regarding accessibility of public buildings have prompted a need for methods and tools to rehabilitate such structures in order to make them accessible to disabled users.
AOUSSAT, Améziane, NELSON, Julien, SEGONDS, Frederic   +2 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A Teaching Experiment in Architectural Design Focused on Efficiency: A Study on the Active and Passive Methods of Site Information Acquisition

Buildings
An important goal in the reform of architectural design education is to instruct students in ways of acquiring relevant site information quickly and efficiently during a design project, and then integrating that information into their architectural ...
Zhi Qiu, Haihui Xie, Su Wang, Lei Wang, Xiang Chen   +4 more
doaj   +1 more source