Results 91 to 100 of about 720,601 (301)

Building Engineering Feasibility Study: Herreshoff Marine Museum [PDF]

open access: yes, 2014
Our design team was supplied with a dozen architectural designs from the students of the Roger Williams University Architectural School. After discussing the strengths and weaknesses of each our team was able to narrow our choices down to one base design
Brunnhoeffer, Gilbert   +6 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Reasoning processes involved in ICT-mediated design communication [PDF]

open access: yes, 2014
Conversational interaction is central to architectural design practice. New information and communication technologies (ICT) change the designer’s traditional way of communicating and interacting.
Bod, Rens   +2 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Educating children in Architecture: XXth architectural narratives troughs toys design [PDF]

open access: yes, 2014
Ponencia presentada a Session 2: La infancia en el medio ambiente urbano / The urban childTeaching processes are, since renaissance, created and supported in order to develope specifically skills for a small part of the society.
Ginoulhiac, Marco
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Enhancing Red Brick Quality Using Corn Cob Ash and Blood Clam Shell Powder

open access: yesRekayasa Sipil
Problems related to the quality of red bricks are still frequently encountered, particularly cracks or damage that occur during the firing process.
Najeelina Putri Adisti   +3 more
doaj   +1 more source

A Pareto Based Genetic Algorithm Model for Sustainable Site Layout Design of Social Housing: SSPM

open access: yesMegaron, 2016
Sustainable architectural design process is more complicated than traditional building design because it has its own regulations that require calculations and comparisons that also need to be considered.
Yazgı Badem Aksoy   +2 more
doaj   +1 more source

Tracking decision-making during architectural design [PDF]

open access: yes, 2005
There is a powerful cocktail of circumstances governing the way decisions are made during the architectural design process of a building project. There is considerable potential for misunderstandings, inappropriate changes, change which give rise to ...
Cerulli, C   +4 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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