Results 91 to 100 of about 9,719,459 (254)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A Method For Investigation Of Effects Of Student’s Cultural Schema On Architectural Design Process In Architectural Design Education [PDF]

, 2010
Tez (Doktora) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2010Thesis (PhD) -- İstanbul Technical University, Institute of Science and Technology, 2010Tezin amacı mimari tasarım sürecinin öğrencilerin sahip olduğu bilişsel şemaları ile ...
Önal, Gökçe Ketizmen
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Ground-Motion Intensity Measures for the Seismic Response of the Roof-Isolated Large-Span Structure

Buildings
Ground-motion intensity measures (IMs), which quantify and describe the characteristics of earthquake ground motion, are of utmost importance in the assessment of seismic risk and the design of resilient structures with large spans.
Wei Zhen, Yikun Qiu, Yanhua Zhang, Wei Li   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Methodology for Computational Architectural Design Based on Biological Principles

, 2013
Biomimicry, where nature is emulated as a basis for design, is a growing area of research in the fields of architecture and engineering. The widespread and practical application of biomimicry as a design approach remains however largely unrealized.
Hanafi, M. (author), ELAHMAR, SALMA ASHRAF SAAD, Fioravanti, A. (author), S.El Ahmar, M. Hanafi, M. Hanai, A. Fioravanti, El Ahmar, S. (author), FIORAVANTI, Antonio   +8 more
core  

Spatial patterns of Geological Culture Villages (Towns) and their influential factors in China

Heritage Science
Geological Culture Villages Towns (GCV(T)s) serve as rich repositories of geological resources, embodying significant historical and cultural values that mirror the dynamic interplay between Earth's evolution and human societies. Despite their importance,
Yunxing Zhang, Zhenyu Zhang, Chenchen Lu, Meiyu Yang, Zhengyu Zhao, Cuihua Gu   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Seismic performance analysis and structural reinforcement design of a complex structural system

Jianzhu Jiegou
In the 1990s，the existing buildings were affected by the service life and the code update. After extending the design service life，it is difficult to meet the load value and seismic performance requirements of the current code. It is of great engineering
XIAN Cheng, HE Xiong, FU Anjun, QI Xin
doaj   +1 more source