Results 111 to 120 of about 145,790 (269)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Design and Construction Research on Retractable Roof of Ningbo Tennis Center

Buildings
The retrofitting of existing stadiums with retractable roof systems presents a complex interdisciplinary challenge, requiring the reconciliation of aged structural capacity with modern performance demands.
Shuizhong Jia, Jianli Xu, Shuo Shi, Ruixiong Li, Wujun Chen   +4 more
doaj   +1 more source

Effort Estimation in Capturing Architectural Knowledge

, 2008
Capturing and using design rationale is becoming a hot topic for software architects, as architectural design decisions are now considered first class entities that should be recorded and documented explicitly.
Francisco Nava, Capilla, Rafael, Carrillo Sanchez, Carlos, Nava, Francisco, Carlos Carrillo, Rafael Capilla   +5 more
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Sketching In Architectural Design Computing

, 2015
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2002Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2002Mimari tasarım sürecinde, tasarımcı fikirlerini geliştirmek ve düşüncelerini ...
Kasapoğlu, Beyza
core  

Computational Design in Distributed Teamwork Using Digital and Non-Digital Tools in Architectural Design Competitions

, 2019
37th Conference on Education and Research in Computer Aided Architectural Design in Europe and 23rd Conference of the Iberoamerican Society Digital Graphics, eCAADe SIGraDi 2019 -- 11 September 2019 through 13 September 2019 -- 275779This paper reports a
Altintas L.E., Kasali A., Dogan F.
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Spatial distribution and influencing factors of traditional villages in South Henan region based on GIS analysis

Journal of Asian Architecture and Building Engineering
Traditional villages serve as significant carriers of Chinese cultural heritage, embodying a rich history and unique regional characteristics, and hold considerable research value.
Xiaofang Bi, Xueyi Peng, Zhaokui Zhuang, Nana Zhu   +3 more
doaj   +1 more source

From HCI to HVRI : how different will the interaction of digital architecture design be?

25th International Conference of the Association for Computer-Aided Architectural Design Research in Asia (CAADRIA 2021), 5-6 August 2020, Faculty of Architecture, Chulalongkorn University, Bangkok, Thailand202505 bcchVersion of ...
Lo, TT, Gao, X
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source