Results 111 to 120 of about 9,719,459 (254)

Enhancing Red Brick Quality Using Corn Cob Ash and Blood Clam Shell Powder

Rekayasa Sipil
Problems related to the quality of red bricks are still frequently encountered, particularly cracks or damage that occur during the firing process.
Najeelina Putri Adisti, Muhammad Ardhiansyah Sofyan Yaqub, Shifa Fauziyah, Fardzanela Suwarto   +3 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Sticky or Not: Adhesion by Architectural Design. [PDF]

ACS Cent Sci, 2023
Dadashi-Silab S, Stache EE.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Potential Assessment and Community Environment Support Strategies for Social Interaction, Based on the Spatiotemporal Behavior of Accompanying Elderly Migrants: A Case Study in Hangzhou

Land
With the growing trend of population mobility and the aging process in China, a significant number of accompanying elderly migrants have moved to major cities.
Zhi Qiu, Bo Jin, Binwei Yun, Zhu Wang, Xincheng Pu   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Augmented reality experience in an architectural design studio. [PDF]

Multimed Tools Appl, 2023
Alp NC, Yazici YE, Oner D.
europepmc   +1 more source

Spatiotemporal changes in human footprints and vegetation coverage and their impacts on the ecosystem services value in the Yangtze River Basin, China

Journal of Freshwater Ecology
In the face of river basin environmental challenges and the urgent need for sustainable development strategies, understanding the complex interactions among ecological services, human activities, and vegetation cover is of paramount importance.
Zhenyu Zhang, Haidong Li, Zhengyu Zhao, Wenjun Zhao, Yuxin Zhang, Yunxing Zhang, Zhigang Li   +6 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Design and Construction Research on Retractable Roof of Ningbo Tennis Center

Buildings
The retrofitting of existing stadiums with retractable roof systems presents a complex interdisciplinary challenge, requiring the reconciliation of aged structural capacity with modern performance demands.
Shuizhong Jia, Jianli Xu, Shuo Shi, Ruixiong Li, Wujun Chen   +4 more
doaj   +1 more source