Results 41 to 50 of about 7,696 (264)
Documenting Software Architecture: Documenting Behavior [PDF]
Abstract : This report represents another milestone of a work in progress: a comprehensive handbook on how to produce high-quality documentation for software architectures. The handbook, tentatively titled Documenting Software Architectures, will be published in early 2002 by Addison-Wesley as part of the Software Engineering Institute (SEI) Series on ...
James Ivers +4 more
openaire +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Multi-Layered Documentation of Heritage Villages: The Case of Tinbak, Qatar
Heritage settlements have long histories that consist of multiple layers of urban layouts, building forms, and culture. Looking at the first layer that formed the initiation stage of the growth becomes a difficult task because of the disguise of other ...
M. Salim Ferwati +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Seminar is part of the activities of the Research of National Interest MIUR PRIN 2008 financed by Italian Ministry for Education University and Research, titled “Complex models for architectural and urban heritage”, with the participation of five ...
Mario Centofanti
doaj +1 more source
The development of applied geodetic techniques for mapping and documentation of historical structures, buildings and sites is an important and vital purpose for contribution of any recording of cultural heritage for any country such as Egypt.
Mariem A. Elhalawani +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Sin dagli albori della sua invenzione, la fotografia ha giocato un ruolo essenziale nella rappresentazione dell’architettura. Caratteristica del nostro tempo, essa ha permesso una nuova visione sul mondo e la definizione di un nuovo linguaggio che ha ...
Alessio Cardaci, Antonella Versaci
doaj +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source

