Results 41 to 50 of about 7,696 (264)

Documenting Software Architecture: Documenting Behavior [PDF]

open access: yes, 2002
Abstract : This report represents another milestone of a work in progress: a comprehensive handbook on how to produce high-quality documentation for software architectures. The handbook, tentatively titled Documenting Software Architectures, will be published in early 2002 by Addison-Wesley as part of the Software Engineering Institute (SEI) Series on ...
James Ivers   +4 more
openaire   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Multi-Layered Documentation of Heritage Villages: The Case of Tinbak, Qatar

open access: yesDesigns, 2021
Heritage settlements have long histories that consist of multiple layers of urban layouts, building forms, and culture. Looking at the first layer that formed the initiation stage of the growth becomes a difficult task because of the disguise of other ...
M. Salim Ferwati   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Architectural survey and documentation for the conservation of historic urban centre. The case study of L’Aquila after the earthquake of 2009.

open access: yesDisegnare con, 2012
The Seminar is part of the activities of the Research of National Interest MIUR PRIN 2008 financed by Italian Ministry for Education University and Research, titled “Complex models for architectural and urban heritage”,  with the participation  of five ...
Mario Centofanti
doaj   +1 more source

Implementation of close range photogrammetry using modern non-metric digital cameras for architectural documentation

open access: yesGeodesy and Cartography, 2021
The development of applied geodetic techniques for mapping and documentation of historical structures, buildings and sites is an important and vital purpose for contribution of any recording of cultural heritage for any country such as Egypt.
Mariem A. Elhalawani   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

L’innovazione nel rilievo fotografico per la conoscenza, la documentazione e la fruizione dei beni culturali

open access: yesDisegnare con, 2013
Sin dagli albori della sua invenzione, la fotografia ha giocato un ruolo essenziale nella rappresentazione dell’architettura. Caratteristica del nostro tempo, essa ha permesso una nuova visione sul mondo e la definizione di un nuovo linguaggio che ha ...
Alessio Cardaci, Antonella Versaci
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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