Results 41 to 50 of about 1,749,840 (251)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Documentation Concept in Architecture “Documentation and Analytic Study of Foreigner’s Architecture in Basra City” [PDF]
Engineering and Technology Journal, 2014 It has been noted that many distinguished buildings are neglected and sometimes destroyed due to misuse, carelessness or environmental factors. Some of these buildings contain evidence of architectural merits that form part of the national heritage ...
Kalel Ibrahim Ali +1 more
doaj +1 more source
Documenting Software Architecture: Documenting Behavior [PDF]
, 2002 Abstract : This report represents another milestone of a work in progress: a comprehensive handbook on how to produce high-quality documentation for software architectures. The handbook, tentatively titled Documenting Software Architectures, will be published in early 2002 by Addison-Wesley as part of the Software Engineering Institute (SEI) Series on ...
James Ivers +4 more
openaire +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
3D Survey with Apple LiDAR Sensor—Test and Assessment for Architectural and Cultural Heritage
Heritage, 2023 The documentation and metric knowledge of architectural and cultural heritage is becoming an increasingly important need, especially concerning the state of degradation of some historical assets and the associated required interventions. In this context,
Giuseppina Vacca
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
College Documentation Bulletin number 2
, 2010 Voir aussi : "Intercultural II : managing cultural diversity in the classroom" (College documentation bulletin, #5, January 2011) disponible dans EDUQ.infoDisponible en français dans EDUQ.info sous le titre "Interculturel I : la formation interculturelle
Lemay, Denyse
core +1 more source
Multi-Layered Documentation of Heritage Villages: The Case of Tinbak, Qatar
Designs, 2021 Heritage settlements have long histories that consist of multiple layers of urban layouts, building forms, and culture. Looking at the first layer that formed the initiation stage of the growth becomes a difficult task because of the disguise of other ...
M. Salim Ferwati +4 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source