Results 41 to 50 of about 7,594 (265)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

From digital photography to the 3D model of the historical architecture

open access: yesDisegnare con, 2013
The Structure from motion procedures have, in recent years, refined to the point of an interesting data acquisition system, also in response to needs for reliable documentation of the different architectural contexts.
Sandro Parrinello, Francesca Picchio
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Reconstructing the Historical Layers of a Colonial Prefabricated Wooden House in Old Calabar (1886–2012): Evidence-Based Workflow for Architectural Restoration

open access: yesBuildings
The importation of prefabricated buildings into colonies was a prevalent practice during the British colonial expansionist venture. However, in post-colonial Nigeria today, many of these prefabricated houses have either been largely modified or have ...
Obafemi A. P. Olukoya
doaj   +1 more source

3D Survey with Apple LiDAR Sensor—Test and Assessment for Architectural and Cultural Heritage

open access: yesHeritage, 2023
The documentation and metric knowledge of architectural and cultural heritage is becoming an increasingly important need, especially concerning the state of degradation of some historical assets and the associated required interventions. In this context,
Giuseppina Vacca
doaj   +1 more source

Software Architecture for Document Anonymization

open access: yesElectronic Notes in Theoretical Computer Science, 2015
AbstractOrganizations often have a dilemma in relation to their documents: ensure confidentiality of the data or publish the information contained in them, for transparency, scientific interest, or other reasons. In this context is that document anonymization arises, i.e.
Horacio Vico, Daniel Calegari
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The Architectural Documentation of British Colonial Prefabricated Wooden Heritage: A Case Study of a Nigerian National Monument

open access: yesArchitecture
The British colonial contact with Nigeria was dotted with diverse paradoxes. In the realm of architecture, it was a period punctuated with the importation of prefabricated buildings into many slave and palm oil trading towns, such as Old Calabar in ...
Obafemi A. P. Olukoya   +2 more
doaj   +1 more source

Multi-Layered Documentation of Heritage Villages: The Case of Tinbak, Qatar

open access: yesDesigns, 2021
Heritage settlements have long histories that consist of multiple layers of urban layouts, building forms, and culture. Looking at the first layer that formed the initiation stage of the growth becomes a difficult task because of the disguise of other ...
M. Salim Ferwati   +4 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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