Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Seminar is part of the activities of the Research of National Interest MIUR PRIN 2008 financed by Italian Ministry for Education University and Research, titled “Complex models for architectural and urban heritage”, with the participation of five ...
Mario Centofanti
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Geospatial Analysis for Decoding Architectural Configuration of Ruins of a Coastal Fort: The Case of Fort Vijaydurg, Konkan, India [PDF]
Documentation and architectural interpretation of ruins of historic buildings is a complex process. Architectural interpretation based on inadequate documentation can result in an undervalued understanding of historic significance and, consequently ...
M. Mane, D. Nakrani
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
INVESTIGATION INTO THE USE OF ACTION CAMERAS IN THE DOCUMENTATION OF ARCHITECTURAL DETAILS – THE CASE STUDY OF A BAROQUE CHAMBER [PDF]
In this paper the possibility of using the Xiaomi 4K action cameras as a low-cost sensor for the generation of high resolution documentation of architecture and architectural elements in the field of Cultural Heritage was analysed.
J. Markiewicz +4 more
doaj +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
The building information modeling for the retrofitting of existing buildings. A case study in the University of Cagliari. [PDF]
Italy's very consistent buildings stock has become the major field for real estate investments and for the related projects and actions. The urge of working on built environment is however facing some crucial issues.
Chiara Tagliabue, Lavinia +6 more
core +1 more source
From ”Sapienza” to “Sapienza, State Archives in Rome”. A looping effect bringing back to the original source communication and culture by innovative and low cost 3D surveying, imaging systems and GIS applications [PDF]
Applicazione di tecnologie mensorie integrate Low Cost,web GIS,applicazione di tecniche di Computational photography per la comunicazione e condivisione dei dati, sistemi di Cloud computing.Archiviazione Grandi DatiHigh Quality survey models, realized ...
Catalani,Giulia +8 more
core +1 more source
Chimneypieces, washbasins, well heads, and sinks by Andrea Palladio represent refined design works following architectural systems on a reduced scale, even if systematic documentation and analysis of them is still limited.
Simone Baldissini, Simone Garagnani
doaj +1 more source

