Results 71 to 80 of about 1,749,840 (251)

Digital Documentation and Analysis of Palladian Microarchitectures: From 3D Models to Knowledge-Based Information Systems

Heritage
Chimneypieces, washbasins, well heads, and sinks by Andrea Palladio represent refined design works following architectural systems on a reduced scale, even if systematic documentation and analysis of them is still limited.
Simone Baldissini, Simone Garagnani
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Bulletin de la documentation collégiale numéro 14 [PDF]

, 2015
Voir aussi : "La formation de la pensée critique : deuxième partie" (Bulletin de la documentation collégiale n°15, janvier 2016), disponible dans EDUQ.infoDisponible en anglais dans EDUQ.info sous le titre "Developing critical thinking : part one ...
Boisvert, Jacques
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Resolving Architectural Mismatches of COTS Through Architectural Reconciliation [PDF]

, 2005
The integration of COTS components into a system under development entails architectural mismatches. These have been tackled, so far, at the component level, through component adaptation techniques, but they also must be tackled at an architectural level
Guelfi, Nicolas, Avgeriou, Paris; id_orcid, Avgeriou, Paris,, Paris Avgeriou, Avgeriou, Paris, Guelfi, Nicolas,, Nicolas Guelfi   +6 more
core   +2 more sources

Bulletin de la documentation collégiale numéro 2

, 2010
Voir aussi : "Interculturel II : la gestion de la diversité ethnique en classe" (Bulletin de la documentation collégiale n°5, janvier 2011), disponible dans EDUQ.infoDisponible en anglais dans EDUQ.info sous le titre "Intercultural I: The Intercultural ...
Lemay, Denyse
core   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Classification of Architectural Heritage Images Using Deep Learning Techniques

Applied Sciences, 2017
The classification of the images taken during the measurement of an architectural asset is an essential task within the digital documentation of cultural heritage.
Jose Llamas, Pedro M. Lerones, Roberto Medina, Eduardo Zalama, Jaime Gómez-García-Bermejo   +4 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source