Results 71 to 80 of about 2,661,935 (362)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Geospatial Analysis for Decoding Architectural Configuration of Ruins of a Coastal Fort: The Case of Fort Vijaydurg, Konkan, India [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information SciencesDocumentation and architectural interpretation of ruins of historic buildings is a complex process. Architectural interpretation based on inadequate documentation can result in an undervalued understanding of historic significance and, consequently ...
M. Mane, D. Nakrani
doaj +1 more source
Analysing how constraints impact architectural decision-making [PDF]
, 2015 Architectural design projects are characterised by a high number of constraints. Along with planning, energy performance and fire safety regulations, current designers have to face constraining factors related to budget, acoustics, orientation, wind ...
De Meyer, Ronald +2 more
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Recording, Documentation, and Information Management for the Conservation of Heritage Places: Guiding Principles [PDF]
, 2008 Provides guidance on integrating recording, documentation, and information management of territories, sites, groups of buildings, or monuments into the conservation process; evaluating proposals; consulting specialists; and controlling ...
Francois LeBlanc +2 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Disegnare con, 2013 Sin dagli albori della sua invenzione, la fotografia ha giocato un ruolo essenziale nella rappresentazione dell’architettura. Caratteristica del nostro tempo, essa ha permesso una nuova visione sul mondo e la definizione di un nuovo linguaggio che ha ...
Alessio Cardaci, Antonella Versaci
doaj +1 more source
FAST AND ACCURATE DOCUMENTATION OF ARCHITECTURAL HERITAGE WITH LOW-COST SPHERICAL PANORAMIC PHOTOGRAPHS FROM 360 CAMERAS [PDF]
, 2023 David Marcos González +3 more
openalex +1 more source
, 2015 This paper describes a method for the recovering of software architectures from a set of similar (but unrelated) software products in binary form. One intention is to drive refactoring into software product lines and combine architecture recovery with ...
Blech, Jan Olaf +5 more
core +2 more sources
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source