Results 121 to 130 of about 5,176,755 (302)
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Thesis: B. Arch., Massachusetts Institute of Technology, Department of Architectural Engineering, 1923Includes bibliographical references (leaf vi).Robert Wales Reno.B. Arch.B. Arch.
Reno, Robert Wales.
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Architectural caring. Architectural qualities from a residential property perspective
A common definition of architectural qualities in general and the values of the qualities in particular can differ significantly in the understanding of different operators in the building construction sector.
Olofsson, Thomas,, Nordwall, Ulf,
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Evaluation of the Sulfate Erosion Resistance in Fly Ash Concrete Subjected to Electric Fields
Right now, there are limited studies on how concrete soil resists sulfate when an electric field and fly ash are used together, and the theory behind stray current engineering protection is not fully developed. This study looks at concrete mixed with fly
Huanqin Liu +5 more
doaj +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Technology Architectural Review [PDF]
Publication of the Massachusetts Institute of Technology Architectural Society. Volume 3.
Massachusetts Institute of Technology. Department of Architecture +1 more
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Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Actors and Vehicles of Architectural Criticism (1)
Actors of Criticism: How the Editors of AD Magazine shaped Architecture Stephen Parnell Newcastle University From its establishment in 1930, architect John Kendall briefly edited Architectural Design (AD) magazine until his death in 1934 when Frederic ...
Mapping Architectural Criticism
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