Results 101 to 110 of about 5,176,755 (302)
An ontology-based approach for modelling architectural styles [PDF]
, 2007 The conceptual modelling of software architectures is of central importance for the quality of a software system. A rich modelling language is required to integrate the different aspects of architecture modelling, such as architectural styles, structural
Wilhelm Hasselbring (8417562) +8 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Architectural Retrofit and Multidisciplinary HVAC Modernization with BIM Methodology: A Study of the Carlos Tortelly Municipal Hospital [PDF]
E3S Web of ConferencesThe modernization of existing public hospitals requires an integrated approach capable of addressing architectural constraints, outdated engineering systems, and evolving regulatory requirements for indoor air quality, energy efficiency, and operational ...
Fugazza Kátia +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
APPLICATION OF VALUE ENGINEERING IN ARCHITECTURAL WORK ON THE LAHAIROI LATERI CHURCH, AMBON CITY
Jurnal PensilEffective construction cost control such as saving construction costs will increase the chances of project success and user satisfaction. The biggest component in construction costs is material.
Ryobi Irfanto +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Архитектура, строительство, транспортThis article addresses the issue of integrating artificial intelligence into curricula and programs in the "Architecture" specialty. Al is considered as an essence of modern creative work and is analyzed as an integrative model in terms of its positive ...
O. Yu. Kostko +2 more
doaj +1 more source