Results 91 to 100 of about 5,176,755 (302)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Mechanically reinforced biotubes for arterial replacement and arteriovenous grafting inspired by architectural engineering. [PDF]

open access: yesSci Adv, 2022
Zhi D   +17 more
europepmc   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Actors and Vehicles of Architectural Criticism (2)

open access: yes, 2016
The Role of Architectural Journals between Medium and the Message Jasna Galjer University of Zagreb The paper explores the case studies of the professional journals in the context of promoting new architectural language and their multilayered roles; from
Mapping Architectural Criticism
core   +1 more source

Towards Quality Assessment in Architectural Education cause study : Architecture Engineering in University of Technology- Iraq

open access: yesAl-Qadisiyah Journal for Engineering Science, 2014
This study is attempt to design development model for architectural education and it's about the process of development of architectural engineering departments in Iraq to improvement performance to arrive appropriate outcomes for work market and ...
Ibrahim J.K. Alyousif   +2 more
doaj  

Enterprise Architecture and Systems Engineering [PDF]

open access: yes, 2003
Factors such as the end of the cold war and increasing globalisation in terms of competition and social responsibility have significantly increased the complexity of events addressed both by governments and by industry. Furthermore, their responses are increasingly more constrained by economic and environmental issues.
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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