Results 71 to 80 of about 432,865 (290)

Form generation and modelling of complex spatial solutions in sacral construction under the influence of modern structural and building technologies and calculation methodologies [PDF]

Дороги і мости
ntroduction. The article addresses the issue of designing complex architectural forms in modern sacred architecture, with a focus on structural feasibility and engineering analysis.
Alexei Yaschenko, Serhii Kelba
doaj   +1 more source

DEVELOPMENT AND IMPLEMENTATION OF INNOVATIVE EDUCATIONAL MODULES ON ARCHITECTURAL PHOTOGRAMMETRY FOR BACHELOR’S DEGREE CURRICULA IN ARCHITECTURE [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Modern specialists in the field of architecture work exclusively in three-dimensional space. At the same time, their training completely ignores the state-of-the-art technologies associated with obtaining three-dimensional models of engineering ...
R. Shults
doaj   +1 more source

Software architectures and Open Source Software: Where can research leverage the most? [PDF]

, 2001
Software architectures have been playing a central role in software engineering research for some years now. They are considered of pivotal importance in the success of complex software systems development.
Arief, B., Gacek, C., Lawrie, T.
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Impact of AI-Powered Platforms and Tools on Architectural Education

Journal of Architecture, Art & Humanistic Science
The integration of artificial intelligence AI into educational processes has been a topic of increasing interest across various disciplines. In the field of architecture, where creativity, design thinking, and technical proficiency are paramount, the use
Assist.Prof. Dr. Maha Fawzy Aly Anber 1Associate Professor of Architecture- Architectural engineering department- Higher Institute of Engineering in Shorouk City- Shorouk Academy- Egypt;
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The Relationship Between The Creation Abilities and Architectural Design Process- Students of Department of Architecture at University of Sulaimany as a Case study

Sulaimani Journal for Engineering Sciences, 2014
Creating is one of the needs of the mental and physical creation , and architectural design has the intercommunication between science and creation to reach student to the creative level especially in architectural design , this research study the ...
Alan Fraidoon Ali, Chro Mohammed Ali
doaj   +1 more source

Architectural authorship in generative design [PDF]

, 2007
The emergence of evolutionary digital design methods, relying on the creative generation of novel forms, has transformed the design process altogether and consequently the role of the architect.
Theodoropoulou, A.
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source