Results 71 to 80 of about 5,176,755 (302)
, 2021 Hélène Jannière and Paolo Scrivano, scientific coordinators of Mapping Architectural Criticism, are very pleased to announce the forthcoming International Conference on Architectural Criticism, On the Duty and Power of Architectural Criticism.
Mapping Architectural Criticism
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Impact of AI-Powered Platforms and Tools on Architectural Education
Journal of Architecture, Art & Humanistic ScienceThe integration of artificial intelligence AI into educational processes has been a topic of increasing interest across various disciplines. In the field of architecture, where creativity, design thinking, and technical proficiency are paramount, the use
Assist.Prof. Dr. Maha Fawzy Aly Anber 1Associate Professor of Architecture- Architectural engineering department- Higher Institute of Engineering in Shorouk City- Shorouk Academy- Egypt;
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
ASEAN Journal on Science and Technology for DevelopmentThis study investigates the transformation of Bubungan Tinggi, a traditional Banjar house with a high roof, into a modern home through the integration of modern facade design with traditional Bubungan Tinggi facade elements.
Nursyarif Agusniansyah +1 more
doaj +1 more source
A perspective on architectural re-engineering
Science of Computer Programming, 2015 Continuous evolution towards very large, heterogeneous, highly dynamic computing systems entails the need for sound and flexible approaches to deal with system modification and re-engineering. The approach proposed in this paper combines an analysis stage, to identify concrete patterns of interaction in legacy code, with an iterative re-engineering ...
Alejandro Sanchez +3 more
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
مجلة النهرين للعلوم الهندسية, 2017 The university education represents one of the civilized basic foundation for societies , for it bears the scientific development flag, as well as it plays fundamental role in serving society, with submitting fundamentals educational and society and ...
Susan Abed Hassan
doaj