Results 51 to 60 of about 5,176,755 (302)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Effort Estimation in Capturing Architectural Knowledge [PDF]

open access: yes, 2008
Capturing and using design rationale is becoming a hot topic for software architects, as architectural design decisions are now considered first class entities that should be recorded and documented explicitly.
Francisco Nava   +5 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

An engineering design knowledge reuse methodology using process modelling [PDF]

open access: yes, 2007
This paper describes an approach for reusing engineering design knowledge. Many previous design knowledge reuse systems focus exclusively on geometrical data, which is often not applicable in early design stages.
Young, Bob   +9 more
core   +1 more source

Review and analysis of education in architectural engineering [PDF]

open access: yesFanāvarī-i āmūzish, 2007
Each program is prepared, approved and implemented according to the policies, goals, facilities, and executive methods of the relevant period. With the advent of new ways of transmitting information and changing facilities and the need to improve the ...
E. Zarghami   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Transforming a Cantilever with Fixed Joints into Trussed Configurations: A Case Study in Creative Design Thinking & Prototyping

open access: yesArchitecture, Civil Engineering, Environment
In the design of structures, joint design significantly influences aesthetics, structural performance, tectonics, and member geometry. In this study, a Y-shaped, polyhedral cantilever with fixed joints was transformed into five different trussed ...
Filz Günther H.   +3 more
doaj   +1 more source

Rock Fracture Response Exposed to Hydraulic Fracturing: Insight into the Effect of Injection Rate on Aperture Pattern

open access: yesAdvances in Materials Science and Engineering, 2022
Injection rate is critical to hydraulic fracturing operation, especially to the hydraulic fracture aperture, which affects the proppant and methane migration.
Bo Zhang   +3 more
doaj   +1 more source

Section II.—Engineering and Architecture [PDF]

open access: yesTransactions of the Sanitary Institute of Great Britain, 1887
n ...
openaire   +1 more source

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