Results 21 to 30 of about 9,070,680 (243)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Operability, Multiscalarity, Diversity, and Complexity in the UNESCO Heritage Regulatory Framework

open access: yesBuildings
The historical genealogy of the heritage regulatory framework, spanning from the 20th century to the present day, provides insights into the continuous socio-cultural transformations within communities.
Adrián Rodríguez-Segura   +2 more
doaj   +1 more source

The Architectural year book, University of Illinois. 15 [PDF]

open access: yes, 1911
Made available in DSpace on 2010-09-21T16:19:17Z (GMT). No. of bitstreams: 2 architecturalyea15univ.pdf: 3980007 bytes, checksum: a6de78626ff0e7fae930b44d614ab662 (MD5) license.txt: 4884 bytes, checksum: ca393d002b14e6043fdd038db22a398d (MD5) Previous ...

core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Transient Permanence

open access: yesRA. Revista de Arquitectura, 2022
There are few places where the tenacious dichotomy of copy and original deconstructs itself more forcefully than in the trajectory we refer to as classical sculpture.
Mari Lending
doaj   +1 more source

Egyptomania in Modern Architectural History [PDF]

open access: yesJournal of Architecture, Art & Humanistic Science
Egyptomania has influenced many domains of Western culture. Since most of the ancient Egyptian heritage falls within the architectural heritage, Egyptomania has inspired the global architectural expression. The research study the impact of Egyptomania on
Hossam ElDin Moustafa ElNour Saleh
doaj   +1 more source

The interactive process of cultural landscape: Taking the trails around Zhengqi Pavilion as an example

open access: yesFrontiers of Architectural Research, 2023
Cultural landscape is a social natural process under which people actively participate in thinking, feeling, and acting. On this basis, their connection with a certain part of the environment in turn affects people's perception of the world and the ...
Mengyao Pan   +3 more
doaj   +1 more source

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