Results 31 to 40 of about 9,070,680 (243)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A post-structural analysis of the architectural education - technology relationship [PDF]
, 2004 This dissertation investigates how technology and architectural education relate to each other, in the broadest possible sense. What are the internal and external factors affecting our understanding and use of technology in architectural education?
Özersay, Fevzi
core +5 more sources
Agrarian voids as dynamic spaces in the contemporary city. The historic orchards of Nerja, Malaga
Ri-vista: Ricerche per la Progettazione del PaesaggioAgriculture and architecture are realities in continuous dialogue in many territories where the productive landscape is an inherent part of the built environment, especially those on a smaller scale with an immediate presence in the city, such as the ...
Celia Chacón Carretón +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Harvard: An Architectural History
, 1985 HARVARD: AN ARCHITECTURAL HISTORY Harvard: An Architectural History (-
Bunting, Bainbridge
core +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Built HeritageThis paper develops a framework for the identification of biocultural indicators of biodiversity in cultural landscapes. To combat the persisting separation and dualistic conceptualisation of nature and culture in the heritage field, the framework views ...
Samantha Tobiáš +2 more
doaj +1 more source
Kungur addresses of the Vakhitovs
Историческая этнологияOne of the cultural heritage sites of the Kungur city (Perm Krai) is known as the “Merchant Vakhitov’s Mansion.” For a long time, it was believed that it was the house where Mullanur Vakhitov, a famous Tatar public figure and revolutionary, was born. His
Olga A. Reneva
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source