Results 31 to 40 of about 455,051 (282)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This position paper looks at the 1964 AIA -ACSA Teacher conference, one that offers us a window into the current anxieties of architectural history survey courses.
Thomas Oommen
doaj +2 more sources
L'histoire assassinée. Manfredo Tafuri and the architecture of the present [PDF]
In recent years the work of Italian architectural historian Manfredo Tafuri has attracted a lot of interest in the world of architectural theory and practice.
Stoppani, T
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Kritisk empiri. Ett historiografiskt perspektiv
The article discusses the possible value of a ”critical empiricism” as the forgotten ”other” of the well-established critical theory. Following Swedish sociologist Johan Asplund, critical empiricism is described as ”seeing what others have not seen”. The
Claes Caldenby
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Agrarian voids as dynamic spaces in the contemporary city. The historic orchards of Nerja, Malaga
Agriculture and architecture are realities in continuous dialogue in many territories where the productive landscape is an inherent part of the built environment, especially those on a smaller scale with an immediate presence in the city, such as the ...
Celia Chacón Carretón +2 more
doaj +1 more source
Brutalism, Film, and Dystopia: The Many (Cinematic) Lives of John Andrews’s Scarborough College
Since its opening to the public in 1965, John Andrews’s megastructure Scarborough College —currently University of Toronto, Scarborough— has received universal acclaim.
Luis-Miguel Lus-Arana +2 more
doaj +1 more source
Architectural Information Modelling in Construction History [PDF]
The past few years show a significant increase in the usage of three-dimensional modelling and semantic description techniques for architectural research purposes.
De Meyer, Ronald +3 more
core +1 more source
Every House on Langland Road – the production of archival, architectural and artistic spaces [PDF]
This article describes an Arts Council England project, undertaken by the author and a photographer, to examine spatial and temporal relations between an art project, its subject and its audience. The project explored and documented the architecture of a
Umney, Darren
core +1 more source

