Results 51 to 60 of about 455,051 (282)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Where do the architects live? [PDF]

open access: yes, 1990
discussion of the extent to which architects can float about history and the inevitable finitude of architectural possibilities from any historical ...
Kolb, David
core  

Plotting the Centre: Bramante’s Drawings for the New St. Peter’s Basilica [PDF]

open access: yes, 2014
This paper examines the concept of 'centre' in the design and symbolism of the new St Peter's Basilica, executed by Donato Bramante in the early 16th century.
Temple, Nicholas
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

“Environmental movement” in architecture and related areas

open access: yesПроект Байкал, 2021
The concept of “environmental approach” in the theory of architecture, urban planning and design is usually used in the singular, but its content is often interpreted in different ways.
Константин Кияненко
doaj   +1 more source

Assessing and valorizing the values of Belgian reconstruction cityscapes today : revisiting Labo S’s engagement with Ypres and Heuvelland [PDF]

open access: yes, 2018
Readily dismissed as inauthentic vieux-neuf, the centrally orchestrated architectural production during the Belgian reconstruction campaigns after the Great War faced a rather cold architecture historical reception in Belgium.
Liefooghe, Maarten
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

De uitdaging van de architectuurhistoricus

open access: yesBulletin KNOB, 2010
This article deals with the challenges for the architectural historian as formulated by the architectural-historical domain during the past three decades. In 1977 an international symposium took place at Utrecht University in which overtures were made to
Freek H. Schmidt
doaj   +1 more source

Extending the design process into the knowledge of the world [PDF]

open access: yes, 2011
Research initiatives throughout history have shown how a designer typically makes associations and references to a vast amount of knowledge based on experiences to make decisions.
De Meyer, Ronald   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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