Results 101 to 110 of about 4,453,047 (296)
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Architecture and Engineering, 2018 Biomimicry is an old approach, but in the scientific conceptualization is new, as an approach of innovation based on the emulation of Nature, in recent years, this approach brings many potential theories and innovations in the architecture field. Indeed,
Yassine Mohammed Benyoucef, Andrey Razin
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Bajo el signo de la esvástica. La Exposición de Arquitectura Moderna alemana en España (1942)
Diacronie. Studi di Storia Contemporanea, 2014 In autumn of 1942, Barcelona received the Exhibition of Modern German Architecture, directed by Albert Speer. The objective of this exhibition was to show to European allies the pharaonic projects of Germany, the Europa’s future new capital, the new ...
Francesc Vilanova i Vila-Abadal es Profesor Titular de Historia Contemporánea en la Universidad Autónoma de Barcelona y Director del Archivo Carles Pi i Sunyer (Fundació Carles Pi i Sunyer d’Estudis Autonòmics i Locals, Barcelon). Miembro del Grup de Recerca en l’Època Franquista (GREF) y del Centre d’Estudis sobre les Èpoques Franquista i Democràtica (UAB-CEFID).
doaj
The problems of high-rise construction in St. Petersburg
Journal of Architecture and Urbanism, 2016 St. Petersburg’s strict limit on building height existed until the 1960s. A small loosening of restrictions occurred only at the end of the 19th century, which formed the “horizontal” silhouette of the city with a few spire accents, domes and factory ...
Leonid Lavrov, Fedor Perov
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Cultural landscape in theory. 1st Part: Centre, core and triangle [PDF]
Urbani Izziv, 2002 The article presents ideas about the close links between architectural forms in theory and practice, as well as the extraordinary ties between the aspects of various disciplines and architectural expression.
Borut Juvanec
doaj
, 2013 Characters like Animal from the Muppet show (a creation by Jim Hen-son) are often illustrations through which we can talk about the quali-ties of the wild, the feral and the natural, in contrast to that which is artificial or built, the man-made. This article, however, would like to focus on the chain.‘Animal,’ the character, offers the
openaire +1 more source