Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Discussion on Integration of Data Warehouse and Big Data
Dianxin kexue, 2015 In view of the traditional enterprise couldn't use such unstructured data efficiently,a big data solutions based on integration of data warehouse and big data was discussed.Based on the theory of data warehouse construction and architecture of the next ...
Juan Yu
doaj
On the Road to Holistic Decision Making in Adaptive Security [PDF]
Technology Innovation Management Review, 2013 Security is a critical concern in today's software systems. Besides the interconnectivity and dynamic nature of network systems, the increasing complexity in modern software systems amplifies the complexity of IT security.
Mahsa Emami-Taba +2 more
doaj
The ethnological and anthropological study of Bežanija at the start of the 21st century: The impact of urban development on boundaries and the perception of a neighbourhood [PDF]
Nasleđe, 2020 Being one of the older settlements in the present-day City of Belgrade, more precisely the municipality of Novi Beograd, Bežanija is a place boasting rich historical, urban planning, and architectural features.
Dražeta Bogdan D., Stankić Mladen D.
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
1951-1952 competition for the Monument to the fallen Jewish soldiers and victims of fascism in the Sephardi cemetery in Belgrade [PDF]
Nasleđe, 2020 In their wish to preserve the memory to the compatriots who lost their lives in the Holocaust, the Jewish community in Yugoslavia started erecting monuments to Jewish civil victims and fallen soldiers as early as the first few post-WWII years.
Stipić Davor
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QAA subject benchmark statement architecture : version for consultation December 2019 [PDF]
, 2019 The Statement is intended to guide lecturers and course leaders in the design of academic courses leading to qualifications in architecture, it will also be useful to those developing other related courses.
Garstecki, P +9 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Ludwig Hilberseimer and Metropolisarchitecture: The Analogue, the Blasé Attitude, the Multitude
Arts, 2018 This article close-reads Modernist architect Ludwig Hilberseimer’s early architectural projects, which employed a language of uniform fenestration, repetition and geometrically reduced typical forms, as embodying Georg Simmel’s blasé ...
Cameron McEwan
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source