Results 111 to 120 of about 6,491,955 (362)
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Discussion on Integration of Data Warehouse and Big Data
Dianxin kexue, 2015 In view of the traditional enterprise couldn't use such unstructured data efficiently,a big data solutions based on integration of data warehouse and big data was discussed.Based on the theory of data warehouse construction and architecture of the next ...
Juan Yu
doaj
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
On the Road to Holistic Decision Making in Adaptive Security [PDF]
Technology Innovation Management Review, 2013 Security is a critical concern in today's software systems. Besides the interconnectivity and dynamic nature of network systems, the increasing complexity in modern software systems amplifies the complexity of IT security.
Mahsa Emami-Taba +2 more
doaj
Minor architecture as major architecture
, 2021 Based on a supposed conceptualization found in Manfredo Tafuri on the notion of "Major Architecture", which only appears only in one of his books and in a way not explicitly developed, a whole series of authors compare the openings of a contrary notion, "Minor Architecture", which would serve to counteract the excesses that the discipline has ...
Tapia Martín, Carlos +1 more
openaire +1 more source
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
The ethnological and anthropological study of Bežanija at the start of the 21st century: The impact of urban development on boundaries and the perception of a neighbourhood [PDF]
Nasleđe, 2020 Being one of the older settlements in the present-day City of Belgrade, more precisely the municipality of Novi Beograd, Bežanija is a place boasting rich historical, urban planning, and architectural features.
Dražeta Bogdan D., Stankić Mladen D.
doaj
Towards an incremental deployment of ERN protocols: a proposal for an E2E-ERN hybrid protocol [PDF]
, 2010 We propose an architecture based on a hybrid E2E-ERN approach to allow incremental deployment of ERN (Explicit Rate Notification) protocols in heterogeneous networks.
Arnal, Fabrice +3 more
core +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
FEBS Open Bio, EarlyView.The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis +3 more
wiley +1 more source