Results 31 to 40 of about 1,087,461 (268)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Education for sustainable development in building higher studies
Advances in Building Education, 2021 UNESCO highlights the crucial role of higher education in achieving each of the 17 SDGs (Sustainable Development Goals). Thus, students should acquire the knowledge and skills needed to promote sustainable development.
Cristina Marieta +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Development of remote control platform for the internet of things infrastructure
Технічна інженерія, 2021 In this article we review a remote control platform for IoT devices. IoT devices have been recently popular all over the world. At the same time, there is a problem of improving the efficiency of designing information systems that will provide access to ...
A.R. , R.V. , K.R.
doaj +1 more source
The PRODNET Architecture [PDF]
, 1999 The PRODNET II consortium designed and implemented an open infrastructure to support industrial virtual enterprises with special focus on the needs of small and medium sized enterprises. The proposed architecture is described summarizing its main components.
Camarinha-Matos, L.M., Afsarmanesh, H.
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Photography and Modern Architecture in Spain
Histories of Postwar Architecture, 2020 Acknowledging the long history of mutual interference between Architecture and Photography, their complex and ubiquitous relationship, and understanding Photography as a relevant artistic and critical research tool, Inaki Bergera ́s work offers new light
Pedro Leão Neto
doaj +1 more source
The CONNECT Architecture [PDF]
, 2011 Current solutions to interoperability remain limited with respect to highly dynamic and heterogeneous environments, where systems encounter one another spontaneously. In this chapter, we introduce the Connect architecture, which puts forward a fundamentally different method to tackle the interoperability problem.
Paul Grace +9 more
openaire +1 more source