Results 51 to 60 of about 1,167,537 (268)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Memaknai Perkembangan Seni dan Arsitektur Gereja: Kontribusi Pemikiran Murray A. Rae terhadap Arsitektur GBKP

open access: yesGema Teologika
The general development of church architecture shows changes in the architectural function of church buildings over time, which not only includes the physical and aesthetic aspects of the building, but also has an important role in representing community
Alosius Des Afriando Sinuraya   +1 more
doaj   +1 more source

A Phenomenological Framework of Architectural Paradigms for the User-Centered Design of Virtual Environments

open access: yesMultimodal Technologies and Interaction, 2018
In some circumstances, immersion in virtual environments with the aid of virtual reality (VR) equipment can create feelings of anxiety in users and be experienced as something “frightening„, “oppressive„, “alienating„,
Matthew E. Gladden
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

La mujer en el espacio pintado: de la Edad Moderna a la Contemporánea / The Woman in the Painted Space: From the Modern to the Contemporary Age

open access: yesAsparkía, 2010
RESUMEN: La pintura es una fuente esencial para la historia y un elemento revelador para la investigación sobre el papel de la mujer en la sociedad a lo largo de la historia.
Rafael Matas Fernandez   +1 more
doaj  

Geometry and construction: mental models and types realized in defence territories

open access: yesDisegnare con, 2012
Two strong concepts like “geometry” and “architecture” can be enhanced if they are correlated to each other, especially if the link between them is the word “construction”.
Anna Marotta
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Società e architettura nella visione satirica

open access: yesAnd, 2022
Esistono frangenti, o meglio potremmo dire che sono sempre esistiti, in cui è molto complesso poter esprimere un’opinione diretta su un argomento. Non solo censure, ma anche oggettiva impossibilità nell’addentrarsi in una dissertazione troppo articolata ...
Maria Elisabetta Ruggiero
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Urbs oblivionalis. Urban Spaces and Terrorism in Italy

open access: yesOcula, 2016
The 14th International Architecture Exhibition (2014), titled Fundamentals and directed by Rem Koolhaas, presented a section called Monditalia: 41 architectural pro-jects concerning specific case studies but together forming a comprehensive portrait of ...
Elena Pirazzoli, Roberto Zancan
doaj  

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