Results 51 to 60 of about 1,071,418 (268)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Asparkía, 2010 RESUMEN: La pintura es una fuente esencial para la historia y un elemento revelador para la investigación sobre el papel de la mujer en la sociedad a lo largo de la historia.
Rafael Matas Fernandez +1 more
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Gema TeologikaThe general development of church architecture shows changes in the architectural function of church buildings over time, which not only includes the physical and aesthetic aspects of the building, but also has an important role in representing community
Alosius Des Afriando Sinuraya +1 more
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Multimodal Technologies and Interaction, 2018 In some circumstances, immersion in virtual environments with the aid of virtual reality (VR) equipment can create feelings of anxiety in users and be experienced as something “frightening„, “oppressive„, “alienating„,
Matthew E. Gladden
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Società e architettura nella visione satirica
And, 2022 Esistono frangenti, o meglio potremmo dire che sono sempre esistiti, in cui è molto complesso poter esprimere un’opinione diretta su un argomento. Non solo censure, ma anche oggettiva impossibilità nell’addentrarsi in una dissertazione troppo articolata ...
Maria Elisabetta Ruggiero
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Geometry and construction: mental models and types realized in defence territories
Disegnare con, 2012 Two strong concepts like “geometry” and “architecture” can be enhanced if they are correlated to each other, especially if the link between them is the word “construction”.
Anna Marotta
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Urbs oblivionalis. Urban Spaces and Terrorism in Italy
Ocula, 2016 The 14th International Architecture Exhibition (2014), titled Fundamentals and directed by Rem Koolhaas, presented a section called Monditalia: 41 architectural pro-jects concerning specific case studies but together forming a comprehensive portrait of ...
Elena Pirazzoli, Roberto Zancan
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